Results 91 to 100 of about 10,751,784 (367)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

The Influence of the European Experts’ Activities on the Development of the Physical and Sports Movement in Yekaterinoslav Governorate (From the Second Half of the 19th Until Early 20th Centuries)

Sport i Turystyka
After the establishment of Ukraine as an independent state, the interest in investigating historical aspects of the development of physical culture and sports both in Ukraine and in its several regions increased significantly. The chronological framework
Ilona Baldzhy, Nina Dolbysheva, Galina Salenko, Nina Kovalenko   +3 more
doaj   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

Some results of physical rehabilitation of victims with consequences of mine-blast injury of lower extremities

Слобожанський науково-спортивний вісник, 2018
Purpose: increase the effectiveness of physical rehabilitation of victims with the consequences of mine-explosive injury of the lower limbs at the polyclinic stage.
Hassan Dandash, Denis Podkopai, Tetiana Podkopai , Charbel Youssef   +3 more
doaj   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

Physical preparedness and functional status of young players in the competition period

Pedagogics, Psychology, Medical-Biological Problems of Physical Training and Sports, 2014
Purpose : evaluate physical preparedness and functional status of young players in the competitive period. Material : the study involved two groups of players. One group - 18 athletes aged 13 years.
Yu.D. Svystun, V.M. Trach, I. M. Chornobaj, Kh. E. Shavel   +3 more
doaj   +1 more source

Physical Education Teachers’ Perspectives in a Changing World: From Future Studies to New Physical Culture

, 2018
The article deals with the physical education teachers’ perspectives in a changing world. Technologies of transhumanism are aimed at expanding human biological capabilities and creating a posthuman, in which natural organs and organ systems are planned ...
O. Voitovska, S. Tolochko
semanticscholar   +1 more source

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

FEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao, Yunlong Li, Lihua Chen, Wenshuo Yang, Yong He, Ye Yang, Dengke Yin, Song Tan   +7 more
wiley   +1 more source

Use of physical culture to increase resistance of sailors to motion sickness [PDF]

From 50% to 70% of sailors are exposed to motion sickness in storms. A program of physical exercises is described and tested for effectiveness in preventing this problem.
Salanin, I. V.
core   +1 more source

Slowing the social sciences of sport: on the possibilities of physical culture

The Social Science of Sport, 2018
Within this paper, we address how the ‘knowledge market’ positions certain ways of knowing over others. We suggest that this questions the very worth and perceived value of the social sciences of sport, let alone allowing for discussion of the ...
Jessica Francombe, D. L. Andrews
semanticscholar   +1 more source