Results 61 to 70 of about 1,281,166 (254)

The built environment and its impact on health outcomes and experiences of patients, significant others and staff—A protocol for a systematic review

open access: yesNursing Open, 2020
Aim This review will identify, evaluate and synthesize the literature related to evidence‐based design of healthcare environments and to identify impacts of the built environment on the outcomes and experiences of patients, significant others and staff ...
Marie Elf   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

The Effects of Spatial Experience and Preferences in Smart Classrooms on Student Learning Engagement

open access: yesBuildings
A smart classroom integrates emerging technologies such as the Internet of Things and cloud computing, optimizes resource allocation, and transforms classroom interaction.
Yibin Ao   +5 more
doaj   +1 more source

“Engaging in my rural community”: perceptions of people aged 85 years and over

open access: yesInternational Journal of Qualitative Studies on Health & Well-Being, 2018
Purpose: Globally, numbers of people aged 85 years and over are increasing. Many older people, including those 85 years and over, are ageing in rural areas. For successful ageing in place, physical and social environments must be appropriate.
Stephen Neville   +4 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

İlkokul Örnekleminde Gürültü Düzeyi Ölçümü ve Öğretmen Görüşleri Açısından Değerlendirilmesi: İzmir Örneği

open access: yesSakarya Üniversitesi Eğitim Fakültesi Dergisi, 2019
Gürültükirliliği insanoğlunda olumsuz fiziksel, fizyolojik ve psikolojik etkileryaratan, arzu edilmeyen sesler olarak hayatımızın her alanına girmiştir.
Mızrap Bulunuz, Murat Merkit
doaj  

The Relationship between Physical Environment (Temperature and Noise) and Work Fatigue in Gas Station Operators in Pontianak City

open access: yesJurnal Info Kesehatan
Work fatigue is a condition that decreases a person's efficiency and endurance at work. It is caused by many individual and external factors, such as the physical work environment, namely temperature and noise. This study aims to analyze the relationship
Ivan Nikola   +2 more
doaj   +1 more source

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

open access: yesMolecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard   +8 more
wiley   +1 more source

Activity-friendly environments for active aging: The physical, social, and technology environments

open access: yesFrontiers in Public Health, 2023
Erja Portegijs, Chanam Lee, Xuemei Zhu
doaj   +1 more source

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