Results 121 to 130 of about 8,303,866 (364)

Enhanced dose prediction for head and neck cancer artificial intelligence‐driven radiotherapy based on transfer learning with limited training data

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Training deep learning dose prediction models for the latest cutting‐edge radiotherapy techniques, such as AI‐based nodal radiotherapy (AINRT) and Daily Adaptive AI‐based nodal radiotherapy (DA‐AINRT), is challenging due to limited data.
Hui‐Ju Wang, Austen Maniscalco, David Sher, Mu‐Han Lin, Steve Jiang, Dan Nguyen   +5 more
wiley   +1 more source

Clinical heterogeneity in a family with flail arm syndrome and review of hnRNPA1‐related spectrum

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1910-1917, December 2022., 2022
Abstract Objective Flail arm syndrome (FAS) is one of the atypical subtypes of amyotrophic lateral sclerosis (ALS). Mutations in hnRNPA1 encoding heterogeneous nuclear ribonucleoprotein (hnRNP) A1 are a rare genetic cause of ALS. Herein, marked clinical heterogeneity of FAS in a pedigree with a known hnRNPA1 variant was described to raise early ...
Xiaochen Han, Feixia Zhan, Yuxin Yao, Li Cao, Jianguo Liu, Sheng Yao   +5 more
wiley   +1 more source

IROC phantoms accurately detect MLC delivery errors

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose We evaluated the impact of random and whole‐bank multileaf collimator (MLC) delivery errors on dosimetric delivery accuracy in the Imaging and Radiation Oncology Core (IROC) phantom audits, as well as differences in delivery accuracy between the IROC phantom prescription and typical clinical fraction sizes.
Sharbacha S. Edward, Julianne M. Pollard‐Larkin, Peter A. Balter, Rebecca M. Howell, Christine B. Peterson, Stephen F. Kry   +5 more
wiley   +1 more source

Recognizing early MRI signs (or their absence) is crucial in diagnosing metachromatic leukodystrophy

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1999-2009, December 2022., 2022
Abstract Objectives Metachromatic leukodystrophy (MLD) has characteristic white matter (WM) changes on brain MRI, which often trigger biochemical and genetic confirmation of the diagnosis. In early or pre‐symptomatic disease stages, these typical MRI changes might be absent, hampering early diagnosis.
Daphne H. Schoenmakers, Shanice Beerepoot, Ingeborg Krägeloh‐Mann, Saskia Elgün, Benjamin Bender, Marjo S. van der Knaap, Nicole I. Wolf, Samuel Groeschel   +7 more
wiley   +1 more source

The effect of multi‐leaf collimator leaf width on VMAT treatment plan quality

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background The advent of volumetric modulated arc therapy (VMAT) in radiotherapy has made it one of the most commonly used techniques in clinical practice. VMAT is the delivery of intensity modulated radiation therapy (IMRT) while the gantry is in motion, and existing literature has shown it has decreased treatment delivery times and the ...
Gregory Sadharanu Peiris, Brendan Whelan, Nicholas Hardcastle, Suzie Lynn Sheehy   +3 more
wiley   +1 more source

Aptamer-based protein molecule detection via cyclic reverse transcription coupling with self-priming hairpin-triggered CRISPR-Cas12a system

Journal of Analytical Science and Technology
Protein biomarkers (e.g. thrombin) are of great significance for the biological process of the organism, and its aberrant expression is closely associated with the development of diseases.
Jie Gao, Xiaoqing Yang
doaj   +1 more source

Exact Bound State Solutions of the Schrodinger Equation for Noncentral Potential via the Nikiforov-Uvarov Method [PDF]

Int. J. Theor. Phys. 48, 2154 (2009), 2007
Exact bound state solutions of the Schrodinger equation for generalized noncentral potential are examined by means of the Nikiforov-Uvarov method. The wavefunctions and the corresponding energy eigenvalues of the system are obtained analytically. The results examined for the potential are compatible with those obtained by the other methods.
arxiv  

XVIII. An examination into the physical consequences of the local alteration of the material of isotropic spheres or spherical shells under uniform surface-pressure [PDF]

, 1894
Charles Chree
openalex   +1 more source

The effect of kV imaging dose on PTV and OAR planning constraints in lung SBRT using stereoscopic/monoscopic real‐time tumor‐monitoring system

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Quantify the impact of additional imaging doses on clinical dose constraints during lung stereotactic body radiotherapy (SBRT) treatment utilizing stereoscopic/monoscopic real‐time tumor monitoring. Materials and Methods Thirty lung SBRT patients treated with the volumetric arc therapy technique were randomly selected from the ...
Ruwan Abeywardhana, Mike Sattarivand
wiley   +1 more source

MiR-451a promotes cell growth, migration and EMT in osteosarcoma by regulating YTHDC1-mediated m6A methylation to activate the AKT/mTOR signaling pathway

Journal of Bone Oncology, 2022
Background: Osteosarcoma is the most prevalent primary malignant bone tumor containing mesenchymal cells with poor prognosis. Being a hot spot of anti-tumor therapy researches, AKT/mammalian target of rapamycin (mTOR) signaling pathway could affect ...
Dong Cao, Shanshan Ge, Mengchun Li
doaj