Results 111 to 120 of about 8,497,984 (308)

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Radiomics-machine learning model for predicting invasiveness of subcentimeter subsolid lung adenocarcinoma: a validation study with external cohort and SHAP interpretability

Frontiers in Oncology
BackgroundPreoperative discrimination of invasive adenocarcinoma (IAC) from pre-invasive lesions in subcentimeter subsolid nodules (SSNs) remains challenging using conventional computed tomography (CT).
Wenfeng Feng, Ruiting Chang, Tiezhi Li, Xiaolong Wang, Zhihong Gao, Xu Yang, Yuling Yin, Yuqiang Zuo   +7 more
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Physical Chemistry: PAC 324

, 2011
Physical Chemistry: PAC 324, supplementary examination January ...
Purcell, W, Sadimenko, A
core  

The Association Between Serum Pentraxin-3 Level at Admission and the Functional Outcome of Patients After Acute Ischemic Stroke: A Meta-Analysis

Balkan Medical Journal
Background: Acute ischemic stroke (AIS) remains a leading cause of disability worldwide, placing a significant burden on patients’ quality of life and healthcare systems.
Yanrong Zhu, Kui Fan, Xujuan Zhao, Kaiwen Hou   +3 more
doaj   +1 more source

The physical examination

Academic Medicine, 1984
H, Schneiderman, A E, Voytovich
openaire   +3 more sources

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Physical Chemistry 11: PHC21E0

, 2014
Examination on Physical Chemistry 11: PHC21E0, Nov ...
Caga, N
core  

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

FEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Physical Chemistry 11: PHC2114

, 2015
Examination on Physical Chemistry 11: PHC2114, Nov ...
Rahman, Z A
core