Results 121 to 130 of about 3,369,384 (303)

A 73‐Year‐Old Man With Several Years of Difficulty Climbing Stairs and Frequent Tripping

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 73‐year‐old man presented with progressive weakness and atrophy predominantly affecting the distal finger flexors and quadriceps muscles. Electrophysiological studies demonstrated mixed myogenic and neurogenic features. Muscle MRI showed inflammatory changes, and muscle biopsy revealed granulomatous myositis with histologic features ...
Mehmet Can Sari, Arens Taga, Sonya Ulrike Steele, Ahmet Hoke   +3 more
wiley   +1 more source

Predicting carotid plaques in metabolic dysfunction-associated steatotic liver disease using machine learning and SHAP interpretation

Scientific Reports
Cardiovascular disease (CVD) remains the most common cause of death worldwide. Carotid plaque is an indicator of subclinical CVDs. Metabolic dysfunction-associated steatotic liver disease (MASLD) is a risk factor for atherosclerotic CVDs.
Shu-Mei Zhai, Xiao-Long Wang, Han Zhang, Yu-Qiang Zuo   +3 more
doaj   +1 more source

Investigating the prognostic significance of examined lymph node count in elderly women with cervical carcinoma: a SEER population-based study

Frontiers in Medicine
ObjectiveThis study aims to explore the prognostic factors including the number of examined lymph nodes (ELNs) for elderly cervical cancer patients who have undergone surgery, and to develop and validate a novel model to predict survival prognosis in ...
Weilan Liu, Kaiyun Qin, Luyang Su, Xiaoyan Duan, Yan Jiang, Caifu Zhao, Wenbo Qi, Congwei Dai   +7 more
doaj   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

Restoring Functional Status: A Long-Term Case Report of Severe Lung and Ventilatory Muscle Pump Dysfunction Involving Recurrent Bacterial Pneumonias [PDF]

, 2012
Background and Purpose: Prolonged mechanical ventilation contributes to immobility and deconditioning making efforts to safely discontinue ventilator support desirable. This case report documents how implementing physical therapy treatment interventions,
Laatsch-Lybeck, Linda Jean, Lipchik, Randolph J, Sobush, Dennis   +2 more
core   +2 more sources

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati, Sami I. Nassar, Shaun A. Nguyen, Patricia L. Gerend, Michael C. Schubert, Michael T. Teixido, Frederick A. Godley, Joel A. Goebel, Cynthia A. Ryan, Habib G. Rizk, Amir Kheradmand   +10 more
wiley   +1 more source

The Association Between Markers of Lipid Homeostasis, Inflammation, and Atherosclerosis Index in Patients with Type 2 Diabetes and Coronary Heart Disease Stratified by Glycemic Control: A Cross-Sectional Study

Journal of Inflammation Research
Ping Yang,1,* Tian Dai,1,* Bo Liu,1 Jun Yin,1 Xiaoli Li,1 Wenxin Zai,1 Hong Zhuang2 1Department of Cardiology, The Sixth Hospital of Wuhan, Affiliated Hospital of Jianghan University, Wuhan, People’s Republic of China; 2Department of ...
Yang P, Dai T, Liu B, Yin J, Li X, Zai W, Zhuang H   +6 more
doaj  

Study on the Correlation Between GDF-15 Levels and a Diagnostic Model for Diabetic Retinopathy

Journal of Diabetes Research
Conclusion: GDF-15 levels are significantly associated with the presence and progression of DR. The logistic regression model demonstrates high predictive value, suggesting that GDF-15 may serve as a promising biomarker for the early diagnosis and ...
Xue-Nan Lian, Xian-Ling Zheng, Ming-Ming Zhu, Zong-Hu Li   +3 more
doaj   +1 more source

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source