Results 91 to 100 of about 2,494,980 (341)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Maintaining physical activity in cardiac rehabilitation [PDF]

, 2006
This chapter describes an intervention that has been used to encourage individuals to remain regularly physically active in exercise-based CR in phases III and IV.The principles of this intervention are also appropriate for allphases of CR.This ...
Hughes, Adrienne, Mutrie, Nanette
core  

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Physical Activity, Yoga, and Exercise Prescription for Postpartum and Midlife Weight Management: A Practical Review for Clinicians

, 2022
Piyush Ranjan, Ananta Gopal Kuanar Baboo, Wareesha Anwar, Archana Kumari, Balaram Pradhan, Satyapriya Maharana, Srikumar Venkataraman   +6 more
openalex   +2 more sources

Exercise epigenetics and the foetal origins of disease [PDF]

, 2014
Exercise epigenetics is a nascent area of research with vast health implications (e.g., from the treatment of obesity-related diseases to beneficially decoupling epigenetic and chronological age).
Dale E, Thomas EW Chalk, William M Brown
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Telehealth-supported exercise/physical activity programs for knee osteoarthritis: A systematic review and meta-analysis [PDF]

, 2023
Chengqi HE, Xiao-Na Xiang, Zezhang Wang, Jiang-Yin Zhang, Ke Li, Qi-Xu Chen, Fa-Shu Xu, Yuewen Zhang, Hongchen He, Siyi Zhu   +9 more
openalex   +1 more source

Evaluation of a standard provision versus an autonomy promotive exercise referral programme: rationale and study design [PDF]

, 2009
Background The National Institute of Clinical Excellence in the UK has recommended that the effectiveness of ongoing exercise referral schemes to promote physical activity should be examined in research trials.
A Kirk, A Zigmond, AJ Issacs, AL Dunn, Amanda Daley, C Jenkinson, D Markland, DA Lawlor, Department of Health, Diabetes Prevention Program Research Group, Diabetes Prevention Program Research Group, EB Kahn, EC Nelson, EL Deci, EL Deci, Frank F Eves, GC Williams, GC Williams, GC Williams, GC Williams, GC Williams, GC Williams, Geoffrey C Williams, I Thune, IM Lee, JA Jolliffe, JF Salis, JK Edmunds, JK Edmunds, JK Edmunds, JM Jakicic, Joan L Duda, Kate Jolly, L Dugdill, LA Talbot, M Hillsdon, M Vuori, MS Fortier, N Mutrie, N Sjosten, Nanette Mutrie, National Institute for Health & Clinical Excellence, NH Williams, Nikos Ntoumanis, PC Rouse, Peter C Rouse, PM Wilson, PM Wilson, PM Wilson, PR Brandon, R Ryan, Rekha Lodhia, S Michie, S Rollnick, SH Kaplan, SM Eldridge, SP Helmrich, TJ Bostic, US Department of Health & Human Services, WL Haskell   +59 more
core   +6 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

What older people tell us about the role of physical activity in the management of depression [PDF]

, 2008
Reports on a study which set out to explore the way in which older people admitted to hospital with depression experience exercise groups and the manner in which they engage in physical activity once discharged.
Cattan, Mima, Wright, Alan
core