Results 171 to 180 of about 2,490,838 (311)

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

Editorial: Exploring the physiological and molecular benefits of physical exercise in cardiovascular diseases. [PDF]

Front Physiol
Improta-Caria AC, Aras Júnior R.
europepmc   +1 more source

Posterior Cortical Atrophy in the Asia‐Pacific: A Report From the PCA Asian Workgroup

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Posterior Cortical Atrophy (PCA) is a distinct dementia syndrome primarily affecting spatial abilities and visual processing. It is associated with degeneration in the posterior part of the brain. PCA is subclassified into PCA‐pure and PCA‐plus syndromes based on consensus criteria.
Yuttachai Likitjaroen, Ya‐Ting Chang, Levinia Lim, Pai‐Yi Chiu, Jung‐Lung Hsu, SangYun Kim, Wataru Narita, Na Young Ryoo, Kyoko Suzuki, Nagaendran Kandiah, Sebastian Crutch, Ming‐Chyi Pai   +11 more
wiley   +1 more source

The dual mediating effect of physical exercise on job performance: a conservation of resources perspective. [PDF]

Front Psychol
Yang Y, Yuan M, Zhou H, Wu X, Xu H.
europepmc   +1 more source

A Preliminary Investigation into the Effect of Continuous Vigorous Exercise and Lifestyle-embedded Physical Activity upon Acute Glycaemic Regulation [PDF]

Background and Purpose Continuous glucose monitoring (CGM) has recently emerged as a new tool for patients with diabetes mellitus to monitor glucose levels and aid maintainenance of euglycaemia.
Esliger, DW, Routen, AC, Rowlands, AV
core  

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Physical exercise mitigates motor and muscular deficits in the 3xTg-AD model of Alzheimer's disease. [PDF]

Front Aging Neurosci
Andrade-Guerrero J, León-Arcia K, Aparicio-Trejo OE, Cuevas-López B, Arias-Carrión O, Díaz-Miranda SY, Soto-Rojas LO.   +6 more
europepmc   +2 more sources

The impact of wearable sports equipment on college students' physical exercise persistence: a mediated model of physical exercise motivation moderated by social support. [PDF]

Front Sports Act Living
Han Y, Wang S, Zhang Z, Fan J.
europepmc   +1 more source

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi, Takumi Nakamura, Ryoma Takahashi, Tetsuya Ueda, Seiji Kinoshita, Chikage Uchida, Takashi Sugawara, Kentaro Hashimoto, Kunihiko Ishizawa, Masakuni Amari, Hiroo Kasahara, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji   +13 more
wiley   +1 more source

Interrelationship Between Physical Exercise and Apical Periodontitis in Trained Rats. [PDF]

Int J Dent
Coaguila-Llerena H, de Souza EON, Solcia ABB, de Assis GG, do Amaral SL, Cerri PS, Faria G.   +6 more
europepmc   +1 more source