Results 71 to 80 of about 59,690 (299)

Carbon isotopes in the ocean model of the Community Earth System Model (CESM1) [PDF]

Geoscientific Model Development, 2015
Carbon isotopes in the ocean are frequently used as paleoclimate proxies and as present-day geochemical ocean tracers. In order to allow a more direct comparison of climate model results with this large and currently underutilized data set, we added ...
A. Jahn, K. Lindsay, X. Giraud, N. Gruber, B. L. Otto-Bliesner, Z. Liu, E. C. Brady   +6 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Influence of polydispersity on the phase behavior of colloidal goethite [PDF]

, 2008
The effect of fractionation on the phase behavior of colloidal goethite dispersions with different polydispersities (17%, 35%, and 55% in length) has been studied by small angle x-ray scattering and transmission electron microscopy.
Physical and Colloid Chemistry 1, van den Pol, E, Physical and Colloid Chemistry 2, A. V. Petukhov, Physical and Colloid Chemistry, Vroege, G.J., Petukhov, A.V., Thies-Weesie, D.M.E., K. Kvashnina, Kvashnina, K., Colloïden en grenslagen, G. J. Vroege, D. M. E. Thies-Weesie, E. van den Pol   +13 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Optical sorting and manipulation of microscopic particles [PDF]

, 2007
Over the last few decades, the use of light to control and manipulate microscopic particles has become widespread. These methods are enabling new areas of research to flourish across the physical and biological sciences.
Milne, Graham
core  

Review of Research and Application of Different Fractionation Techniques in Oil and Fat Processing

Liang you shipin ke-ji
Fat fractionation, as a key physical refining technology for enhancing oil quality and added value, has evolved from basic process optimization to innovative integration of multiple technologies.
GU Ya-xin, HE Dong-ping, ZHOU Teng, YIN Jiao-jiao   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Molecular weight fractionation by confinement of polymer in one-dimensional pillar[5]arene channels [PDF]

, 2019
Confinement of polymers in nano-spaces can induce unique molecular dynamics and properties. Here we show molecular weight fractionation by the confinement of single polymer chains of poly(ethylene oxide) (PEO) in the one-dimensional (1D) channels of ...
Kojima, Ryosuke, Yagyu, Masafumi, Akine, Shigehisa, Kakuta, Takahiro, Ogoshi, Tomoki, Sakata, Yoko, Yamagishi, Tada-aki, Mizuno, Motohiro, Hirao, Hajime, Doitomi, Kazuki, Sueto, Ryuta, Tummanapelli, Anil Kumar   +11 more
core   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Axial Variations and Entry Effects in a Pressure Screen [PDF]

, 2007
Pressure screens are used for contaminant removal and fibre length fractionation in the production of pulp and paper products. Axial variations and entry effects in the screen are known to occur and these variations have not been adequately quantified.
Martin John Atkins, Atkins, Martin John
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