Results 91 to 100 of about 29,786,065 (334)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Modelica - A Language for Physical System Modeling, Visualization and Interaction [PDF]
, 1999 Modelica is an object-oriented language for modeling of large, complex and heterogeneous physical systems. It is suited for multi-domain modeling, for example for modeling of mechatronics including cars, aircrafts and industrial robots which typically ...
Elmqvist, H., Mattsson, S. E., Otter, M.
core
Mapping of dissipative particle dynamics in fluctuating hydrodynamics simulations
, 2008 Dissipative particle dynamics (DPD) is a novel particle method for mesoscale modeling of complex fluids. DPD particles are often thought to represent packets of real atoms, and the physical scale probed in DPD models are determined by the mapping of DPD ...
He, P., Qiao, R.
core +1 more source
Physics-Based Explosion Modeling
Graphical Models, 2001 Summary: Explosions are among the most common special effects employed in the entertainment industry. Producing real explosions, however, is costly and potentially dangerous and special effects technicians have been turning to software to generate explosion sequences.
Bashforth, Byron, Yang, Yee-Hong
openaire +2 more sources
Physical Modeling of Suspended Sediment Deposition in Marine Intakes of Nuclear Power Plants
, 2015 This paper deals with the problems associated with the design and operation of once–through or combined water cooling systems of nuclear power plants using sea water.
Nikolay Arefiev +16 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Results in PhysicsThe evolution of a polydisperse ensemble of prolate and oblate ellipsoidal crystals in a supercooled one-component melt is theoretically studied. The volume growth rates for prolate and oblate ellipsoids are analytically found and compared at the same ...
Dmitri V. Alexandrov +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
The Study of Geomechanical Condition of Unstable Rocks in the Vicinity of Mine Working Junctions
Горные науки и технологии, 2019 The relevance of research of material strain nature based on physical models equivalent to rocks is substantiated. To identify the dependencies and mechanism of unstable rock strain in the vicinity of mine working junctions, an experimental technique has
V. V. Basov
doaj +1 more source