Results 41 to 50 of about 513,704 (220)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

SPECIAL PHYSICAL FITNESS RESEARCH OF BASKETBALL CLUB “TAMBOV” PLAYERS

open access: yesВестник Тамбовского университета. Серия: Гуманитарные науки, 2016
For more than a century basketball as a sport game has got a huge number of fans all over the world. Inherent high emotionality and entertainment, a variety of manifestations of physical qualities and motor skills, intellectual abilities and mental ...
Vera Borisovna Boldyreva   +2 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Narration the Lived Experiences of Career Couples of Family Function, Health Dimension

open access: yesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2020
Introduction: Family function has been changed by the couple's simultaneous employment and presents particular problems for the family and the couples. One of the dimensions that is strongly influenced by the functioning of the working couple's family is
Rohollah Rahimi   +3 more
doaj  

Connection Formulae between Ellipsoidal and Spherical Harmonics with Applications to Fluid Dynamics and Electromagnetic Scattering

open access: yesAdvances in Mathematical Physics, 2015
The environment of the ellipsoidal system, significantly more complex than the spherical one, provides the necessary settings for tackling boundary value problems in anisotropic space.
Michael Doschoris, Panayiotis Vafeas
doaj   +1 more source

Review of Eidsheim, Nina Sun. 2015. Sensing Sound: Singing and Lis-tening as Vibrational Practice.

open access: yesCurrent Musicology, 2017
One challenge of writing about music has often been summed up with the question “where is the music?”The asker gets at the impossibility of isolat-ing the musical text to be studied.
Lucie Vágnerová
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Physical Activity as a Health Need

open access: yesCentral European Journal of Sport Sciences and Medicine, 2017
The scientific concept of human needs has an interdisciplinary nature and is associated with the standards of living and development, health and disease status, quality of life, and life satisfaction.
Aleksander Olejnik   +3 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy