Results 61 to 70 of about 3,121,428 (243)
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
SPECIAL PHYSICAL FITNESS RESEARCH OF BASKETBALL CLUB “TAMBOV” PLAYERS
For more than a century basketball as a sport game has got a huge number of fans all over the world. Inherent high emotionality and entertainment, a variety of manifestations of physical qualities and motor skills, intellectual abilities and mental ...
Vera Borisovna Boldyreva +2 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Narration the Lived Experiences of Career Couples of Family Function, Health Dimension
Introduction: Family function has been changed by the couple's simultaneous employment and presents particular problems for the family and the couples. One of the dimensions that is strongly influenced by the functioning of the working couple's family is
Rohollah Rahimi +3 more
doaj
The environment of the ellipsoidal system, significantly more complex than the spherical one, provides the necessary settings for tackling boundary value problems in anisotropic space.
Michael Doschoris, Panayiotis Vafeas
doaj +1 more source
Physical Activity as a Health Need
The scientific concept of human needs has an interdisciplinary nature and is associated with the standards of living and development, health and disease status, quality of life, and life satisfaction.
Aleksander Olejnik +3 more
doaj +1 more source
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Review of Eidsheim, Nina Sun. 2015. Sensing Sound: Singing and Lis-tening as Vibrational Practice.
One challenge of writing about music has often been summed up with the question “where is the music?”The asker gets at the impossibility of isolat-ing the musical text to be studied.
Lucie Vágnerová
doaj +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source

