Results 41 to 50 of about 58,517 (295)

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

open access: yesFEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke   +2 more
wiley   +1 more source

A Regional Aerosol Model for the Oceanic Area around Eastern China Based on Aerosol Robotic Network (AERONET)

open access: yesRemote Sensing
A regional aerosol model can complement globally averaged models and improve the accuracy of atmospheric numerical models in local applications. This study established a seasonal aerosol model based on data from the Aerosol Robotic Network (AERONET) of ...
Shunping Chen   +8 more
doaj   +1 more source

Preflight Evaluation of the Environmental Trace Gases Monitoring Instrument with Nadir and Limb Modes (EMI-NL) Based on Measurements of Standard NO2 Sample Gas

open access: yesRemote Sensing, 2022
Hyperspectral observations are used to retrieve high-resolution horizontal distribution and vertical profiles of trace gases (O3, NO2, HCHO, and SO2), thereby playing a vital role in monitoring the spatio-temporal distribution and transportation of ...
Taiping Yang   +5 more
doaj   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

Record Low Arctic Stratospheric Ozone in Spring 2020: Measurements of Ground-Based Differential Optical Absorption Spectroscopy in Ny-Ålesund during 2017–2021

open access: yesRemote Sensing, 2023
The Arctic stratospheric ozone depletion event in spring 2020 was the most severe compared with previous years. We retrieved the critical indicator ozone vertical column density (VCD) using zenith scattered light differential optical absorption ...
Qidi Li   +5 more
doaj   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Spatial Fluctuations of Optical Turbulence Strength in a Laboratory Turbulence Simulator

open access: yesPhotonics
Controlled turbulence simulators in the laboratory have been extensively employed to investigate turbulence effects on light propagation in the atmosphere, driven by some advanced optical engineering such as remote sensing, energy-delivery systems, and ...
Yanling Li   +6 more
doaj   +1 more source

Analysis of Optical Turbulence over the South China Sea Using Balloon-Borne Microthermal Data and ERA5 Data

open access: yesRemote Sensing, 2022
It is very useful for adaptive optics (AO) systems to have appropriate knowledge of optical turbulence. However, due to the limitations of space and time, it is difficult to obtain turbulence parameters, especially in the far sea area. In this paper, the
Manman Xu   +3 more
doaj   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

Real-Time Three-Dimensional Tracking of Distant Moving Objects Using Non-Imaging Single-Pixel LiDAR

open access: yesRemote Sensing
The real-time tracking of moving objects has extensive applications in various domains. Existing tracking methods typically utilize video image processing, but their performance is limited due to the high information throughput and computational ...
Zijun Guo   +6 more
doaj   +1 more source

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