Results 101 to 110 of about 1,609,519 (260)

Indicators of Successful Career Transitions from Physical Sciences and Engineering to Biomedical Research. [PDF]

Curr Genomics, 2021
Beer MA.
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Assessing the Organic Acids-solubilized Collagen Derived from the Skin of Unicornfish (Naso reticulatus Randall, 2011) on Physicochemical and Structural Characteristics: Toward Alternative Source for Industrial Applications

ASEAN Journal on Science and Technology for Development
Converting skin by-product of unicornfish (Naso reticulatus Randall, 2011) into a valuable commodity like collagen is a good strategy to explore alternative sources for land-based animals.
Dayang Fazrianie Harianto, Abdul Aziz Jaziri, Rossita Shapawi, Ruzaidi Azli Mohd Mokhtar, Wan Norhana Md. Noordin, Masmunira Rambli, Nurul Huda   +6 more
doaj   +1 more source

U.S. postdoctoral careers in life sciences, physical sciences and engineering: Government, industry, and academia. [PDF]

PLoS One, 2022
Denton M, Borrego M, Knight DB.
europepmc   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Application of Three of Selected Medicinal Plant Extracts in Brunei Darussalam to Improve Shelf Life of Poultry Product

ASEAN Journal on Science and Technology for Development
. Bioactive compounds from plant derived in food application become increasingly in demand due to natural and nutritionally safe products. Due to some issues concerning food safety on the excessive use of synthetic preservatives; the present study aims ...
Hazirah Abd Hamid, Namasivayam Navaranjan, Zohrah Sulaiman, Aida Maryam binti Hj Basri   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Recent Advance in Biodegradable Packaging from Banana Plant Feedstock: A Comprehensive Review

ASEAN Journal on Science and Technology for Development
This review focuses on recent advances in biodegradable packaging derived from banana plant waste, highlighting its pivotal role in addressing environmental concerns linked to conventional packaging materials. The shift toward sustainable packaging stems
M. Atiq Juani, Namasivayam Navaranjan
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Technological Advancements in Brunei’s Local Agriculture and Fisheries Companies: An Exploratory Study Based on Field Observations

ASEAN Journal on Science and Technology for Development
This exploratory study, through seven field observations and interviews, investigates the technological advancements transforming Brunei's agricultural landscape in pursuit of local production augmentation and self-sufficiency.
Muhammad Firdaus Mujibuddin Syah Mustafa, Navaranjan Namasivayam, Hong Shyang Pei, Fatnin Farhanah Alihan, Amni Sahilah Sahrullamzah, Khairina Umairah Takiyaudin   +5 more
doaj   +1 more source