Results 101 to 110 of about 5,133,590 (283)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

The Biological/Physical Sciences Divide, and the Age of Unreason

open access: yesSubstantia, 2017
D’Arcy Thompson in On Growth and Form tells us that the early founders of the cell theory of biology, and the physiologists believed that progress in their sciences depended critically on our knowledge of molecular forces.
Barry W. Ninham
doaj   +1 more source

Ropelength of tight polygonal knots

open access: yes, 2004
A physical interpretation of the rope simulated by the SONO algorithm is presented. Properties of the tight polygonal knots delivered by the algorithm are analyzed. An algorithm for bounding the ropelength of a smooth inscribed knot is shown. Two ways of
Eric   +3 more
core   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

A Comparison of Mental Health Status between Students of Two Faculties of Alzahra University: Physical Education vs. Educational Sciences and Psychology [PDF]

open access: yesTaṣvīr-i salāmat, 2011
Background and objectives : This study aimed to compare mental health status between students of two faculties of Alzahra University: physical education vs. educational sciences and psychology.
Elham Baghban Baghestan   +1 more
doaj  

THE ROLE OF PHYSICAL EXPERIMENTS IN POPULARIZATION OF EXACT SCIENCES

open access: yesOdessa Astronomical Publications, 2007
Physical experiments play crucial role in exact sciences.We test our theories which we try give account of the world by experiments. On the one hand, themselves are an inexorable judge which one judge our conceptions about function of the world and on ...
S. Ledvinka, J. Pisala
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Synergistic enhancement in Ag quantum dot modified TiO2 via interfacial electron transfer channels and LSPR

open access: yesiScience
Summary: Environmental pollution poses a pressing global challenge, and photocatalysis represents a promising remediation technology. However, photogenerated carrier recombination remains a critical limitation.
Yangfan Du   +8 more
doaj   +1 more source

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