Results 61 to 70 of about 1,528,950 (267)

The Impact of College Physical Sciences on Mental Rotation Ability

open access: diamond, 2023
Abigail Walters   +3 more
openalex   +2 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

A Comparison of Mental Health Status between Students of Two Faculties of Alzahra University: Physical Education vs. Educational Sciences and Psychology [PDF]

open access: yesTaṣvīr-i salāmat, 2011
Background and objectives : This study aimed to compare mental health status between students of two faculties of Alzahra University: physical education vs. educational sciences and psychology.
Elham Baghban Baghestan   +1 more
doaj  

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Assessing river discharge dynamics through relative surface water extent changes in river basins

open access: yesiScience
Summary: Surface water in rivers is vital for human society. However, our current understanding of the dynamics and drivers of river flows relies predominantly on stream gauging data, which are limited in spatial coverage and involve significant costs ...
Feng Mao   +4 more
doaj   +1 more source

THE ROLE OF PHYSICAL EXPERIMENTS IN POPULARIZATION OF EXACT SCIENCES

open access: yesOdessa Astronomical Publications, 2007
Physical experiments play crucial role in exact sciences.We test our theories which we try give account of the world by experiments. On the one hand, themselves are an inexorable judge which one judge our conceptions about function of the world and on ...
S. Ledvinka, J. Pisala
doaj   +1 more source

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