Results 71 to 80 of about 5,133,590 (283)
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Index to 1984 NASA Tech Briefs, volume 9, numbers 1-4 [PDF]
Short announcements of new technology derived from the R&D activities of NASA are presented. These briefs emphasize information considered likely to be transferrable across industrial, regional, or disciplinary lines and are issued to encourage ...
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The research problem lies in answering some question what is the reality of transformational leadership in some faculties of physical education and Iraqi sports sciences from the teachers 'point of view and the aim of the research is to prepare a ...
مروة خالد خزعل أ.د. بشرى كاظم عبد الرضا
doaj +1 more source
Strongly self-absorbing C*-dynamical systems, III [PDF]
The work presented in this paper has benefited from a visit to the Department of Mathematics at the University of Kyoto in January 2016, and I would like to express my gratitude to Masaki Izumi for the hospitality and support.
Barlak +30 more
core +3 more sources
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Introducing article numbering to Journal of the Nigerian Society of Physical Sciences
Nigerian Society of Physical Sciences
doaj +1 more source
Summary: The study compares the effectiveness of yoga practice duration in managing type 2 diabetes (T2D) among the Asian population. Out of 664 results, 22 randomized clinical trials were identified with 1,720 participants, aged 18–65 years, with ...
Anu Mahajan, Jhanvee Shah, Arti Muley
doaj +1 more source
XX. Meaning in the Physical Sciences
The twentieth century has seen two major revolutions in our theories of physics concerning nature, and these have made us change many of our concepts about the terms in which nature can be described.
Bloom, Robert L. +6 more
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