Results 61 to 70 of about 18,003,298 (302)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Minutes: Committee for the Study of Physical Facilities for the Health Sciences, 1965-1967
, 1967 The committee for the study of physical facilities for the health sciences was established in 1964 to study the needs of physical facilities, buildings and laboratories for the University's health sciences and medical programs.University of Minnesota ...
University of Minnesota. Committee for the Study of Physical Facilities for the Health Sciences
core
Physical activity when young provides lifelong benefits to cortical bone size and strength in men
, 2014 The skeleton shows greatest plasticity to physical activity-related mechanical loads during youth but is more at risk for failure during aging. Do the skeletal benefits of physical activity during youth persist with aging?
Warden, Stuart J. +6 more
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
iScienceSummary: The study compares the effectiveness of yoga practice duration in managing type 2 diabetes (T2D) among the Asian population. Out of 664 results, 22 randomized clinical trials were identified with 1,720 participants, aged 18–65 years, with ...
Anu Mahajan, Jhanvee Shah, Arti Muley
doaj +1 more source
Enterprise in Physical Science
New Directions, 2003 With an increasing emphasis on enterprise and innovation in government directives, it is timely to consider the embedding of enterprise activities within the physical science curriculum. We have piloted a course “Physics in an Enterprise Culture”, and are now expanding to embrace project work and dual degree schemes.
openaire +2 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
ASEAN Journal on Science and Technology for DevelopmentThe phenomenon of sea level rise (SLR) is a global issue affecting coastal areas. This study analyzes SLR and land deformation in the subduction zone of the Tanimbar Islands, specifically the coastal regions of Adaut on Selaru Island and Saumlaki on ...
Ibnu A. Azies +3 more
doaj +1 more source