Results 71 to 80 of about 3,661,712 (303)

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Mixed ether bath for electrodeposition of aluminum [PDF]

, 1969
Anisole added to the bath mixture improves Brenner aluminum plating bath technique. Mixture has lower bath vapor-pressure and the electro-deposits obtained have greater physical strength than deposits from the Brenner ...
Lui, K.
core   +1 more source

Fairness in Water Quality: A Descriptive Approach [PDF]

, 1994
Muscle strength is important for firefighters work capacity. Laboratory tests used for measurements of muscle strength, however, are complicated, expensive and time consuming.
Lindberg, Ann-Sofie, Malm, Christer, Oksa, Juha   +2 more
core   +3 more sources

The Importance of Physical Strength to Human Males [PDF]

Human Nature, 2012
Fighting ability, although recognized as fundamental to intrasexual competition in many nonhuman species, has received little attention as an explanatory variable in the social sciences. Multiple lines of evidence from archaeology, criminology, anthropology, physiology, and psychology suggest that fighting ability was a crucial aspect of intrasexual ...
Sell, Aaron, S. E. Hone, Liana, Pound, Nicholas   +2 more
openaire   +3 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Ageing, physical function, and the diurnal rhythms of cortisol and dehydroepiandrosterone [PDF]

, 2012
The present study examined the relationship between ageing, physical function and the diurnal rhythms of cortisol and dehydroepiandrosterone (DHEA). Participants were 36 community dwelling older adults aged between 65-86 years old.
Aardal, Adam, Ahmed, Ahn, Anna C. Phillips, Belanger, Berg, Berg, Berkman, Brown, Brown, Buford, Butcher, Chahal, Cherniack, Cohen, Deuschle, Donaldson, Douglas Carroll, Edwards, Edwards, Erosheva, Fried, Garde, Goodyer, Granger, Hucklebridge, Jennifer L.J. Heaney, Joseph, Kirschbaum, Kirschbaum, Kraemer, Kroboth, Kunz-Ebrecht, Labrie, Luz, Nicholl, Nouri, Orentreich, Parker, Peeters, Phillips, Pruessner, Pruessner, Rockwood, Schürmeyer, Sjogren, Smyth, Straub, Turner-Cobb, VanCauter, Varadhan, Voznesensky, Walston, Walston, Whembolua, Wolf, Yen   +57 more
core   +1 more source

Physical Processes at High Field Strengths [PDF]

Physica Scripta, 1987
The availability of extraordinarily bright femtosecond ultraviolet sources is rapidly extending the study of atomic responses into an unexplored regime for which the electric field strength is considerably in excess of an atomic unit. As this regime is approached, experiments studying multiple ionization, photoelectron spectra, harmonically produced ...
openaire   +1 more source

Intercompartmental communication in senescence

FEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz, Eleanor J. Wind, Jixiang Leng, Myriam Gorospe   +3 more
wiley   +1 more source

Subjective assessment and biochemical evaluation of traction therapy in women with chronic low back pain: does body mass index matter? A clinical study

BMC Musculoskeletal Disorders, 2023
Background Apart from the positive effect of lumbar traction on structural changes within the spine in patients with low back pain, it is likely that therapeutic effects are correlated with pain biomarkers in the blood.
Marzena Ratajczak, Michał Wendt, Ewa Śliwicka, Damian Skrypnik, Jacek Zieliński, Krzysztof Kusy, Piotr Krutki, Małgorzata Waszak   +7 more
doaj   +1 more source