Results 31 to 40 of about 1,162,787 (260)

Stability of Naked Nucleic Acids under Physical Treatment and Powder Formation: Suitability for Development as Dry Powder Formulations for Inhalation

Pharmaceutics, 2023
A number of functional nucleic acids, including plasmid DNA (pDNA) and small interfering RNA (siRNA), have been attracting increasing attention as new therapeutic modalities worldwide.
Tomoyuki Okuda, Maki Okazaki, Akihiko Hayano, Hirokazu Okamoto   +3 more
doaj   +1 more source

Evaluation of the Effect of Dopamine D2 Receptor Antagonist on the Spermatogenesis Process in Rats Under Physical or Psychological Stress and Their Offspring

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2020
Background and Objectives: Stress disrupts the neurotransmitter release and reproduction. Dopamine (D) is one of the most important neurotransmitters, and its receptor (D2R) has been identified in testis. The use of effective drugs on reproductive system
Shahla Amiri, Farrin Babaei-Balderlou, Gholamreza Najafi   +2 more
doaj  

Models and Methods to Investigate Acute Stress Responses in Cattle

Animals, 2015
There is a growing appreciation within the livestock industry and throughout society that animal stress is an important issue that must be addressed.
Yi Chen, Ryan Arsenault, Scott Napper, Philip Griebel   +3 more
doaj   +1 more source

Neurobiology of Physical Environmental Stress.

Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene), 1992
Although effects of physical environmental stress, including noise and whole-body vibration, on human psychological activities and emotion are not negligible for environmental and occupational hygiene, attempts to elucidate their physiological and biomedical mechanisms have been not made until recently.
openaire   +3 more sources

An Improved Model of Physical and Emotional Social Defeat: Different Effects on Social Behavior and Body Weight of Adolescent Mice by Interaction With Social Support

Frontiers in Psychiatry, 2018
Social stress is a prevalent etiological environmental factor that can affect health, especially during adolescence. Either experiencing or witnessing a traumatic event during adolescence can increase the risk of psychiatric disorders, such as PTSD.
Man Li, Man Li, Man Li, Man Li, Hang Xu, Hang Xu, Weiwen Wang, Weiwen Wang   +7 more
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

The functional detrained heart as the problem of modern students: the constitutional approach in diagnostics and the alternative variants of the pharmacologic correction

Лечащий Врач, 2021
The article describes the issues of somatotypological determination in functioning of cardiovascular system and its adaptation potential in response to steep demands — physical efforts.
P. K. Boichenko, A. A. Tjurenkov, A. R. Batova, V. P. Poteryakhin, V. V. Dolgopolov   +4 more
doaj  

Obesity as a noticeable cause of physical stress; A study on relationship of physical exertion and cardiovascular parameters

International Journal of Endorsing Health Science Research, 2016
Introduction Physical tension is a response to environmental pressures, needs or demands or any vigorous bodily activity leading in altering physiological responses, is counted as physical stress such as aerobics, work outs, injury or aches.
Ammara Farooq, Muzna Patel, Sadaf Ahmed, Shamoon Noushad   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source