Results 41 to 50 of about 1,162,787 (260)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

OSTEOFITOSIS VERTEBRAL EN POBLACIONES PREHISPÁNICAS DE SAN PEDRO DE ATACAMA, NORTE DE CHILE

Estudios Atacameños
Se estudió la osteofitosis vertebral como indicador de estrés físico en grupos humanos prehistóricos de San Pedro de Atacama, durante los períodos Medio (400 DC - 1000 DC) e Intermedio Tardío (1000 DC - 1450 DC).
Rocío López-Barrales, Mark Hubbe, Eugenio Aspillaga, Walter A Neves, Hermann M Niemeyer   +4 more
doaj   +1 more source

Binding Strength of Gram-Positive Bacterial Adhesins

Frontiers in Microbiology, 2020
Bacterial pathogens are equipped with specialized surface-exposed proteins that bind strongly to ligands on host tissues and biomaterials. These adhesins play critical roles during infection, especially during the early step of adhesion where the cells ...
Yves F. Dufrêne, Albertus Viljoen
doaj   +1 more source

Physical activity and stress coping in the elderly [PDF]

Einstein (São Paulo), 2010
ABSTRACT Objective: To analyze the value of a physical activity program on stress coping of the elderly. Methods: Intervention study with a group of 18 elderly people referred by the Geriatric Service of the Hospital das Clinicas of the Universidade de Sao Paulo, who attended a supervised exercise program, evaluated by the human activity profile and ...
Andréa, Fernando de, Lanuez, Fernanda Varkala, Machado, Adriana Nunes, Jacob Filho, Wilson   +3 more
openaire   +6 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Hypoxia and anoxia effects on alcohol dehydrogenase activity and hemoglobin content in Chironomus riparius Meigen, 1804

Journal of Limnology, 2016
The metabolic effects of low oxygen content on alcohol-dehydrogenase (ADH) activity and hemoglobin (Hb) concentration were investigated in IV-instar larvae of Chironomus riparius (Diptera: Chironomidae) from an Italian stream.
Valentina Grazioli, Bruno Rossaro, Paolo Parenti, Roberto Giacchini, Valeria Lencioni   +4 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Similarities and differences in carotid artery, hemodynamic, and autonomic reactivity induced by mental stress or cold in adults: A randomized crossover study

Physiological Reports
The cold pressor test (CPT) is used to investigate cardiovascular and autonomic responses, while the Stroop color‐word test (Stroop) is also used for this purpose, although its vascular effects require further understanding.
Francisco J. Fensterseifer, Iara G. Teixeira, Welliton Oracz, Richard E. Filipini, Francine Stein, Guilherme F. Speretta   +5 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source