Results 51 to 60 of about 309,816 (316)

THE EFFECTS OF A SHORT TERM HIGH-INTENSITY CIRCUIT TRAINING EXERCISE IN UNIVERSITY STUDENTS

International Journal of Physiotherapy, 2015
Background: Physical inactivity is one non-communicable disease threatening to become the fourth leading risk factor for global mortality. Japan is no exception especially in the younger population.
Rie Takakura, Kubo Masayoshi , Yuji Tsubota   +2 more
doaj   +1 more source

Music Therapy Techniques for Memory Stabilization in Diverse Dementias [PDF]

, 2018
Music contains certain unmistakable healing properties pertaining specifically to the matured body and soul affected by various types of dementia. Music therapy aids in memory retention or the retarding of the loss of mental function as a result of ...
Shotts, Amanda
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Shoulder and Elbow Synergy for Lateral Epicondylalgia Management: A Case Report [PDF]

Journal of Clinical and Diagnostic Research
Lateral epicondylalgia, commonly known as tennis elbow, is a chronic overuse injury characterised by acute inflammation at the common wrist extensor origin, resulting in pain.
Maheshkumar Baladaniya, Purva Gulrandhe
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Frequency of Musculoskeletal Discomfort and Peripheral Neuropathies in Clinical Physical Therapists

Journal Riphah College of Rehabilitation Sciences, 2023
Objectives: To determine the frequency of musculoskeletal discomfort and peripheral neuropathies in clinically practicing physical therapist and to assess their health related quality of life.
Ayesha Ali, Iqra Imtiaz, Muhammad Mehdi Abbas, Ashar Rafi, Asif Khan, Namal Shahzadi   +5 more
doaj  

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

مقایسه تاثیر اولتراتون واولتراسوند در سندرم کانال کارپ ایدیوپاتیک خفیف یا متوسط

مجله پژوهش در علوم توانبخشی, 2011
مقدمه: سندرم کانال کارپ یکی از شایعترین نوروپاتی های انسدادی است که درمان های متعددی (جراحی و غیر جراحی) برای آن پیشنهاد شده است. در فیزیوتراپی درمان های متنوعی برای آن پیشنهاد شده است که از جمله می توان استفاده از اسپلینت، نوروموبیلیزیشن، لیزر ...
Hamid Azade, Alireza Jamshidi fard, Fatemeh Ansari, Soghra Jokar   +3 more
doaj   +1 more source