Results 61 to 70 of about 5,661,908 (250)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
International Journal of Child Development and Mental Health, 2018 The Bayley-III Screening test is one of the most worldwide used standardized assessments for young children aged between 1-42 months, however, it is less well-known in Thailand.
Mattana Angsupaisal +2 more
doaj
Frequency of Musculoskeletal Discomfort and Peripheral Neuropathies in Clinical Physical Therapists
Journal Riphah College of Rehabilitation Sciences, 2023 Objectives: To determine the frequency of musculoskeletal discomfort and peripheral neuropathies in clinically practicing physical therapist and to assess their health related quality of life.
Ayesha Ali +5 more
doaj
, 2019 Title from PDF caption (viewed on December 23, 2019).Senate Bill 855 (2019) directs professional licensing boards to study the manner in which persons who are immigrants or refugees become authorized to practice occupation or profession.This archived ...
core
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
A challenge in health professions is training practitioners to navigate health care complexities, promote health, optimize outcomes, and advance their field.
Osborne, Raine +8 more
core +3 more sources
THE EFFECTS OF A SHORT TERM HIGH-INTENSITY CIRCUIT TRAINING EXERCISE IN UNIVERSITY STUDENTS
International Journal of Physiotherapy, 2015 Background: Physical inactivity is one non-communicable disease threatening to become the fourth leading risk factor for global mortality. Japan is no exception especially in the younger population.
Rie Takakura +2 more
doaj +1 more source
Physical Therapist Licensing Board: change of director audit
, 2003 This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from caption"Report no. 2003-21.""June 9, 2003."OrDocs
core