Results 81 to 90 of about 5,661,908 (250)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Urdu Translation of Denver Sacroiliac Joint Questionnaire (DSIJQ) and Its Validity and Reliability in Sacroiliac Joint Dysfunction (SIJD) Patients: A Cross-Sectional Study

Journal Riphah College of Rehabilitation Sciences
Background: Sacroiliac joint dysfunction (SIJD) is a significant contributor of both chronic low back pain and disability. The Denver Sacroiliac Joint Questionnaire (DSIJQ) is a condition-specific tool designed to evaluate severity of symptoms and ...
Sumbal Salik, Somia Faisal, Laila Niaz Khan, Raheel Munawar   +3 more
doaj  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

مقایسه تاثیر اولتراتون واولتراسوند در سندرم کانال کارپ ایدیوپاتیک خفیف یا متوسط

مجله پژوهش در علوم توانبخشی, 2011
مقدمه: سندرم کانال کارپ یکی از شایعترین نوروپاتی های انسدادی است که درمان های متعددی (جراحی و غیر جراحی) برای آن پیشنهاد شده است. در فیزیوتراپی درمان های متنوعی برای آن پیشنهاد شده است که از جمله می توان استفاده از اسپلینت، نوروموبیلیزیشن، لیزر ...
Hamid Azade, Alireza Jamshidi fard, Fatemeh Ansari, Soghra Jokar   +3 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Frequency of Scapular Dyskinesis and its Association with Shoulder Pain in Gym-Going Females in Hayatabad: A Cross-Sectional Survey

Journal Riphah College of Rehabilitation Sciences
Background: Scapular dyskinesis is a common issue among individuals who engage in regular gym activities. As the scapula provides a stable base for movement, alterations in its positioning or motion can impair shoulder function.
Hira Anwar, Zarghuna Taj, Bakhtawar Malik, Syeda Afsheen Hasnain Daud, Najia Zulfiqar   +4 more
doaj  

Effect of Chronic Low Back Pain on Balance and Functional Mobility in Women above 40 Years

Journal Riphah College of Rehabilitation Sciences, 2021
Objectives: To find the number of individuals with disturbed balance and impaired functional mobility, associated with chronic low back pain. Methodology: It was a cross sectional observational study of seventy female patients with age 40 years or ...
khabeer fatima, Zahid Mehmood Bhatti, Iqra Khan, Ubaid Ullah Akbar   +3 more
doaj  

The hominid thumb and its influence on the employment during evolution

Reumatismo, 2019
Not ...
J.H. Villafañe, R. Cantero-Tellez, P. Berjano   +2 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Physical therapist education and the labor market in brazil: advances and challenges

, 2019
Background: In Brazil, the number of physical therapy education programs and, consequently, of professionals has been growing for the past 20 years.
Daniela Virgínia Vaz, Rosana Ferreira Sampaio, Juliana de Melo Ocarino, Jorge Alexandre Barbosa Neves, Vera Regina Fernandes da Silva Marães, Rodrigo Affonso de Albuquerque Nobrega, Lucas Wan Der Maas   +6 more
core   +1 more source