Results 31 to 40 of about 2,419,871 (314)

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

Molecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin, Kjersti Tjensvoll, Karin Hestnes Edland, Satu Oltedal, Herish Garresori, Bjørnar Gilje, Saga Ekedal, Trygve Eftestøl, Jan Terje Kvaløy, Filip Janku, Oddmund Nordgård   +10 more
wiley   +1 more source

The effectiveness of the cardiac resynchronization in a patient with ischemic cardiomyopathy [PDF]

, 2018
Cardiac resynchronization therapy (CRT) in multiple and large trials has been demonstrated to improve symptoms and decrease hospitalization and mortality of patients when used in addition to optimal medical therapy.
Bătăiosu, Constantin, Donoiu, Ionuț, Florescu, Cristina, Paraschiv, Alina, Tudorașcu, Diana R., Târtea, Elena-Anca   +5 more
core   +4 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Effects of whole-body vibration on quadriceps and hamstring muscle strength, endurance, and power in children with hemiparetic cerebral palsy: a randomized controlled study

Bulletin of Faculty of Physical Therapy, 2021
Background Hemiplegic cerebral palsy (CP) enormously affects the quadriceps and hamstring muscles. It causes weakness in the affected lower-extremity muscles in addition to muscle imbalance and inadequate power production, especially in the ankle plantar-
Rania G. Hegazy, Amr Almaz Abdel-aziem, Eman I. El Hadidy, Yosra M. Ali   +3 more
doaj   +1 more source

Physical Therapy Department Newsletter for Winter 2014 [PDF]

, 2014
The Winter 2014 (Edition 1, Volume 1) issue of Physical Therapy, a periodical focused on the Physical Therapy Department within the College of Human Science and ...
URI Physical Therapy Department
core   +1 more source

Age-related differences in exercise and quality of life among breast cancer survivors [PDF]

, 2010
Purpose: Physical activity has become a focus of cancer recovery research as it has the potential to reduce treatment-related burden and optimize health-related quality of life (HRQoL).
Arndt, BETH NEWMAN, Brady, Brucker, Connell, Coster, Courneya, Courneya, Daley, Di Sipio, Drouin, Hayes, Hayes, Holick, Holmes, Kelsey, Kimsey, King, Kopelman, McNeely, McPherson, Meyerhardt, Milne, Mock, Mutrie, Pinto, Pinto, SANDRA C. HAYES, Schmitz, Schwartz, SHEREE A. HARRISON, Stevinson, Thewes, van Dam, Wenzel   +34 more
core   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Physical Fitness of Physical Therapy Students [PDF]

, 1983
Physical fitness norms do not exist for physical therapists or physical therapy students. This lack, in part, reflects the complexity of physical fitness and the scarcity of data reported on physical fitness norms of other populations.
Fehring, Richard, Sobush, Dennis
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

The Effects of Exercise and Activity-Based Physical Therapy on Bone after Spinal Cord Injury [PDF]

, 2022
Tommy W. Sutor, Jayachandra R. Kura, Alex J. Mattingly, Dana M. Otzel, Joshua F. Yarrow   +4 more
openalex   +1 more source