Results 71 to 80 of about 675,115 (366)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Today\u27s Fibromyalgia [PDF]

open access: yes, 2019
Fibromyalgia is a chronic musculoskeletal disorder which results in widespread pain, fatigue, cognitive difficulties, and emotional distress (CDC, 2017). It is also associated with abnormal pain processing.
Glennon, McKenzie K.
core   +1 more source

The human prerogative: a critical analysis of evidence-based and other paradigms of care in substance abuse treatment [PDF]

open access: yes, 2010
Present-day substance abuse treatment is characterized by a compelling demand for applying evidence-based interventions. Vehement discussions between policymakers, practitioners and researchers illustrate this clash of differing paradigms.
Autrique, Annemarie   +3 more
core   +2 more sources

Physical therapies for Achilles tendinopathy: systematic review and meta-analysis

open access: yesJournal of Foot and Ankle Research, 2012
Background Achilles tendinopathy (AT) is a common condition, causing considerable morbidity in athletes and non-athletes alike. Conservative or physical therapies are accepted as first-line management of AT; however, despite a growing volume of research,
Sussmilch-Leitch Samuel P   +4 more
doaj   +1 more source

A pilot study evaluating the effect of early physical therapy on pain and disabilities after breast cancer surgery: Prospective randomized control trail

open access: yesBreast, 2021
Background: Morbidity of the shoulders after breast cancer (BC) surgery is a common side effect that includes; persistent pain, function limitation, and decreased range of motion (ROM).
Ifat Klein   +3 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

The Pairing of Trigger Point Dry Needling with Rehabilitation Techniques [PDF]

open access: yes, 2019
Trigger point dry needling is a manual treatment modality used for individuals experiencing tightness, pain, and inhibited range of motion in any region of the body.
Kotze, Karle
core   +1 more source

Predicting and Comparing the Subjective Health Experience of Older Cancer Survivors and Non‐Cancer Survivors: A Modeling Approach

open access: yesAging and Cancer, EarlyView.
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst   +4 more
wiley   +1 more source

Efficacy of interspinous device versus surgical decompression in the treatment of lumbar spinal stenosis: a modified network analysis. [PDF]

open access: yes, 2011
Study designSystematic review using a modified network analysis.ObjectivesTo compare the effectiveness and morbidity of interspinous-device placement versus surgical decompression for the treatment of lumbar spinal stenosis.SummaryTraditionally, the most
Chou, Dean   +3 more
core   +1 more source

THE ROLE OF THE PHYSIOTHERAPIST IN PALLIATIVE CARE IN ONCOLOGY PATIENTS: A SYSTEMATIC REVIEW

open access: yesJournal of Cancer Rehabilitation
Background Physiotherapy in palliative oncology patients is less discussed in literature and needs to be thoroughly investigated. Aim The aim of this study was to gather and analyze the available evidence on the effect of physiotherapy in oncology ...
Luna Gauchez, PT   +7 more
doaj   +1 more source

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