Results 91 to 100 of about 165,108 (216)

Intrapersonal, social-cognitive and physical environmental variables related to context-specific sitting time in adults : a one-year follow-up study [PDF]

open access: yes, 2016
Background: Investigating associations between socio-ecological variables and context-specific sitting time in adults can support the development of future interventions.
Greet Cardon   +9 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

The effect of psychometric variables in predicting physical activity behavior among diabetes mellitus type-2 patients

open access: yes, 2017
Abraham Tamirat Gizaw, Fira Abamecha Ababulgu, Lakew Abebe Gebretsadik, Getachew Kiros Abraha Department of Health Education and Behavioral Science, College of Public Health and Medical Sciences, Jimma University, Jimma, Ethiopia ...
Abebe Gebretsadik L   +3 more
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Complex symmetric weighted composition operators on the Fock space in several variables

open access: yes, 2017
We characterize all selfadjoint as well as all unitary anti-linear weighted composition operators acting on the Fock space . Then we obtain a complete description of anti-linear weighted composition operators that are conjugations. These results allow us
Khoi, Le Hai   +3 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Economic Determinants of Participation in Physical Activity and Sport [PDF]

open access: yes
This paper examines the economic determinants of participation in physical activity by developing and analyzing a consumer choice model of participation and by testing the predictions of this model using data drawn from the Behavioral Risk Factor ...
Jane E. Ruseski, Brad R. Humphreys
core  

The Effect of Specific Pre Season Training Package on Selected Physical Fitness Variables

open access: yes, 2012
The purpose of the study was to find out the effect of a pre-season training package on selected physical fitness variables of Volleyball players. In total 100 numbers of students were taken as subjects and were divided equally (50 each) into two groups ...
Ranjan Mishra, Sakti   +1 more
core   +1 more source

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