Results 41 to 50 of about 165,108 (216)

HARPA: Tackling physically induced performance variability

Design, Automation & Test in Europe Conference & Exhibition (DATE), 2017, 2017
Continuously increasing application demands on both High Performance Computing (HPC) and Embedded Systems (ES) are driving the IC manufacturing industry on an everlasting scaling of devices in silicon. Nevertheless, integration and miniaturization of transistors comes with an important and non-negligible trade-off: time-zero and time-dependent ...
Zompakis, N., Noltsis, M., Ndreu, L., Hadjilambrou, Z., Englezakis, P., Nikolaou, P., Portero, A., Libutti, S., Massari, G., Sassi, F., Bacchini, A., Nicopoulos, Chrysostomos A., Sazeides, Y., Vavrik, R., Golasowski, M., Sevcik, J., Vondrak, V., Catthoor, F., Fornaciari, W., Soudris, D., Zompakis, N., Noltsis, M., Ndreu, L., Hadjilambrou, Z., Englezakis, P., Nikolaou, P., Portero, A., Libutti, S., Massari, G., Sassi, F., Bacchini, A., Nicopoulos, Chrysostomos A., Sazeides, Y., Vavrik, R., Golasowski, M., Sevcik, J., Vondrak, V., Catthoor, F., Fornaciari, W., Soudris, D.   +39 more
openaire   +3 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Physical test variables, overview.

, 2015
The training-set performed all physical tests, the prediction-set performed physical tests in bold style. Some physical tests included several variables.
Henrik Antti (222864), Christer Malm (429323), Ann-Sofie Lindberg (429320), Juha Oksa (429321)   +3 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Variables and their physical meaning.

, 2019
Variables and their physical meaning.
Afroza Shirin (6490526), Isaac Klickstein (6490532), Francesco Sorrentino (479016), John Russell (2721583), Fabio Della Rossa (6490529)   +4 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Utility of accelerometers to measure physical activity in children attending an obesity treatment intervention [PDF]

, 2011
Objectives. To investigate the use of accelerometers to monitor change in physical activity in a childhood obesity treatment intervention. Methods. 28 children aged 7–13 taking part in “Families for Health” were asked to wear an accelerometer (Actigraph)
Robertson, Wendy, Stewart-Brown, Sarah, Wendy Robertson, Michelle Oldfield, Wilcock, Elizabeth, Elizabeth Wilcock, Margaret Thorogood, Horton, Elizabeth; id_orcid, Thorogood, Margaret, Oldfield, Michelle, Stewart-Brown, Sarah L., Sarah Stewart-Brown   +11 more
core   +1 more source

Fibromyalgia : Associations Between Fat Infiltration, Physical Capacity, and Clinical Variables

, 2022
Background: Obesity is a risk factor for the development of fibromyalgia (FM) and generally most studies report increased Body Mass Index (BMI) in FM. Obesity in FM is associated with a worse clinical presentation.
Gerdle, Björn, Lundberg, Peter,, Bengtsson, Ann,, Forsgren, Mikael,, Dahlqvist Leinhard, Olof,, Ghafouri, Bijar, Lundberg, Peter, Lund, Eva,, Ghafouri, Bijar,, Lund, Eva, Dahlqvist Leinhard, Olof, Forsgren, Mikael, Forsgren, Mikael Fredrik, Gerdle, Björn,, Bengtsson, Ann   +14 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Change in Depression, Confidence, and Physical Function Among Older Adults With Mild Cognitive Impairment

, 2019
Background and Purpose Nearly a quarter of those in the US over age 71 experience mild cognitive impairment (MCI). Persons with MCI (PwMCI) battle depression and progressive disengagement from daily activities, which contribute to participation ...
Altenburger, Peter, Lu, Yvonne, Jennifer L. Ellis, Peter Altenburger, Ellis, Jennifer L., Yvonne Lu   +5 more
core   +1 more source