Results 31 to 40 of about 9,253,090 (290)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Developments in euthanasia practice in the Netherlands: Balancing professional responsibility and the patient’s autonomy

European Journal of General Practice, 2019
In 2015, euthanasia accounted for 4.5% of deaths in the Netherlands, of which 93% were performed by a GP. Historically, a conflict of physician’s duties—to alleviate unbearable suffering and at the same time preserve the patient’s life—is central to the ...
Pauline S. C. Kouwenhoven, Ghislaine J. M. W. van Thiel, Agnes van der Heide, Judith A. C. Rietjens, Johannes J. M. van Delden   +4 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

O médico na indústria farmacêutica.

Acta Médica Portuguesa, 1993
The physician's role in the pharmaceutical industry has changed over the past years. This change is a consequence of several factors, namely the evolution of the industry itself, the legislative and regulatory changes in this particular area, the ...
I D Lopes, M V Gomes, J C Branco
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Prostate cancer radiation therapy: A physician's perspective. [PDF]

, 2016
Prostate cancer is the second most common cancer in men and a major cause of cancer deaths worldwide. Ionizing radiation has played a substantial role in the curative treatment of this disease.
Souhami, Luis, Dal Pra, Alan
core   +1 more source

Physicians’ roles in competency-based teaching: Do students recognize them?

GMS Journal for Medical Education, 2018
Introduction: Imparting the concept of physician’s roles with the help of new teaching formats is becoming increasingly important in medical education.
Pippel, Elvira, Narciß, Elisabeth, Obertacke, Udo, Strohmer, Renate, Schüttpelz-Brauns, Katrin   +4 more
doaj   +1 more source

Predictors of Physician’s Empathy: The Role of Spiritual Well-being, Dispositional Perspectives, and Psychological Well-being

Oman Medical Journal, 2020
Objectives: Empathy is a core component of an efficient physician-patient relationship. Although students’ preexisting medical views may influence responses to physician-patient relationship, there is little knowledge about the psychological predictive ...
Angela Hamidia, Pouria Amiri, Mahbobeh Faramarzi, Mohamah Hadi Yadollahpour, Soraya Khafri   +4 more
doaj   +1 more source

Medical students’ learning experience and participation in communities of practice at municipal emergency care units in the primary health care system: a qualitative study

BMC Medical Education, 2022
Background Medical education has been criticised for not adapting to changes in society, health care and technology. Internationally, it is necessary to strengthen primary health care services to accommodate the growing number of patients.
Solveig Giske, Marit Kvangarsnes, Bodil J. Landstad, Torstein Hole, Berit Misund Dahl   +4 more
doaj   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source