Results 51 to 60 of about 28,464 (292)

Lethal left cardiac thromboembolism in infant: A rare complication of pulmonary tuberculosis

open access: yesRespiratory Medicine Case Reports, 2019
If acute or severe infectious are know that risk factors for venous thromboembolism (VTE), the role active tuberculosis is ill defined, despite different case reports and many small case series have proposed an association between VTE and chronic ...
N.N.M. Razafimanjato   +5 more
doaj   +1 more source

Driving retirement: the role of the physician [PDF]

open access: yesCanadian Medical Association Journal, 2006
In the United States, licensed drivers over the age of 65 years today number more than 20 million — a figure that will increase substantially over the next few decades.[1][1] Certain age-associated conditions such as dementia will lessen the expected increase, since, for reasons of safety ...
David B, Carr   +2 more
openaire   +2 more sources

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li   +11 more
wiley   +1 more source

Sequential Treatment of Sorafenib-Regorafenib Versus Sorafenib-Physician's Choice: A Propensity Score-Matched Analysis

open access: yes, 2021
Background: Regorafenib has been shown to improve clinical outcomes compared to placebo, becoming a standard second-line therapy for sorafenib-progressed and -tolerated hepatocellular carcinoma (HCC) patients.
Ryoo, Baek-Yeol   +46 more
core   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Dementia : Patient's Right and Physician's Role

open access: yesSiriraj Medical Journal, 2003
An elderly Thai widow with progressive dementia was transferred to Siriraj Hospital for properly continued supportive treatment. Due to the course of the disease, she lacked the ability to make any valid decision related to giving consent to medical ...
Supawon Srettabunjong   +3 more
doaj  

Patient Understanding of the Resident Physician's Role in Orthopaedics

open access: yesSurgiColl
# Objectives Patients at teaching hospitals interact with resident physicians, yet their understanding of residents’ roles varies. Prior studies in other specialties have found gaps in patient knowledge of the medical training hierarchy.
Jeffton Pierre   +3 more
doaj   +1 more source

Watching Out for Older Drivers

open access: yesMedEdPORTAL, 2006
Motor vehicle accidents are the leading cause of injury-related deaths among adults age 65 to 74. This risk for traffic fatalities may triple as the numbers of older drivers increases in the coming years.
Samuel Durso
doaj   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito   +8 more
wiley   +1 more source

The Physician's Assistant

open access: yes, 2018
THE SHORTAGE, maldistribution, and inefficient use of physicians, particularly primary physicians, recently has received much attention, Suggested solutions focus either on increasing the number of physicians or on improving the efficiency with which ...
Judith R. Lave (347795)   +1 more
core   +1 more source

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