Results 171 to 180 of about 1,473,116 (296)
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Interactive effects of shoe style and verbal cues on perceptions of female physicians' personal attributes [PDF]
OBJECTIVE: To determine whether shoe style has any effect on perceptions of a female physician's personal characteristics when viewed alongside a transcript of a short outpatient consultation.
Moudraia, Dr Olga +3 more
core
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Background Antimicrobial resistance (AMR) is acknowledged by the World Health Organization as a top-ten danger to public health. In Canada, AMR accounted for over 12,900 deaths in 2019.
Nicole Kain +7 more
doaj +1 more source
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Comprehensiveness of care by family physicians in Edmonton [PDF]
Andrew J Cave¹, Lakshmi Parameswaran²¹Department of Family Medicine, University of Alberta, Edmonton, Alberta, Canada; ²Mater Misericordiae University Hospital, Dublin, IrelandIntroduction: The scope of practice by ...
Parameswaran L, Cave AJ
core
Vegan diet, processed foods, and body weight: a secondary analysis of a randomized clinical trial
Low-fat plant-based diets cause weight loss in clinical trials. However, many foods are highly processed, raising the question as to their effect on body weight.
Hana Kahleova +6 more
doaj +1 more source
Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source
Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall +16 more
wiley +1 more source

