Results 51 to 60 of about 1,473,116 (296)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The Spatial Distribution of Physicians in the United States: A Review of the Literature [PDF]

open access: yes, 1977
One manifestation of a contemporary concern with equality in the provision of health care services is the growing interest that appears to be developing in the spatial location of medical manpower. There is no evidence that any country has ever achieved,
Butler, J.R.
core  

Institutional animal care and use committees and the challenges of evaluating animal research proposals

open access: yesResearch Integrity and Peer Review
Background In the U.S. and many other countries, animal use in research, testing, and education is under the purview of Institutional Animal Care and Use Committees or similar bodies.
John J. Pippin   +8 more
doaj   +1 more source

Additional file 1: of Physiciansâ pharmacogenomics information needs and seeking behavior: a study with case vignettes

open access: yes, 2017
Case Vignettes. (DOCX 69Â kb)
Heale, Bret   +4 more
openaire   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Comparison of wellness/burnout between primary care pediatricians and pediatric subspecialists

open access: yesBMC Health Services Research
Background Burnout in the field of healthcare is among the most important challenges encountered across our workforce. Provider burnout increases the risk of personal manifestations of stress, impaired job performance, and provider turnover.
Suzanne Kaseta   +4 more
doaj   +1 more source

Additional file 3: of Physiciansâ pharmacogenomics information needs and seeking behavior: a study with case vignettes

open access: yes, 2017
Need Codes grouped by Theme. (DOCX 43 kb)
Heale, Bret   +4 more
openaire   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Invitation to a Special Meeting of the College of Physicians with speakers Marie Curie and Robert Abbe [PDF]

open access: yes, 1921
An invitation to a special meeting at The College of Physicians of Philadelphia in which Marie Curie presented the Piezo-Electric Apparatus which she and her husband Pierre used in their early experiments with radium.
The College of Physicians of Philadelphia
core  

Women Physicians' Narratives About Being in Ethically Difficult Care Situations in Paediatrics [PDF]

open access: yes, 2000
This study is part of a comprehensive investigation of ethical thinking among male and female physicians and nurses. Nine women physicians with different levels of expertise, working in various wards in paediatric clinics at two of the university ...
Sorlie, Venke   +3 more
core   +1 more source

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