Results 141 to 150 of about 3,276,266 (409)

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
wiley   +1 more source

An optimized protocol to detect high‐throughput DNA methylation from custom targeted sequences on 96 samples simultaneously

FEBS Open Bio, EarlyView.
Workflow of a high‐throughput technology for epigenotyping of differentially methylated CpGs in specific regions of the genome. The protocol works with small amounts of DNA extracted from blood or semen. The protocol consists of both enzymatic conversion of unmethylated cytosines and capture by hybridization with a custom panel.
Nathalie Iannuccelli, Sophie Valière, Julien Sarry, Cécile Donnadieu, Julie Demars   +4 more
wiley   +1 more source

The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions

FEBS Open Bio, EarlyView.
Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh, Esther Lee, Soo‐A Kim   +2 more
wiley   +1 more source

Vegan diet, processed foods, and body weight: a secondary analysis of a randomized clinical trial

Nutrition & Metabolism
Low-fat plant-based diets cause weight loss in clinical trials. However, many foods are highly processed, raising the question as to their effect on body weight.
Hana Kahleova, Tatiana Znayenko-Miller, Arathi Jayaraman, Giulianna Motoa, Laura Chiavaroli, Richard Holubkov, Neal D. Barnard   +6 more
doaj   +1 more source

Society of Physicians at Kazan University. Vol. 24, No. 10 (1928)

, 1928

openalex   +2 more sources

Teaching Python with team‐based learning: using cloud‐based notebooks for interactive coding education

FEBS Open Bio, EarlyView.
This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley   +1 more source

Corrigendum: Core Competencies for Pharmaceutical Physicians and Drug Development Scientists

Frontiers in Pharmacology, 2015
Honorio eSilva, Peter eStonier, Fritz eBuhler, Jean Paul eDeslypere, Domenico eCriscuolo, Gerfried eNell, Joao eMassud, Stewart eGeary, Johanna eSchenk, Sandor eKerpel-Fronius, Greg eKoski, Norbert eClemens, Ingrid eKlingmann, Gustavo eKesselring, Rudolf evan Olden, Dominique eDubois   +15 more
doaj   +1 more source

Diploma in Ophthalmic Medicine and Surgery of the Royal College of Physicians of London and the Royal College of Surgeons of England

, 1921

openalex   +1 more source

Menthol‐like cooling compounds, including (R)‐(‐)‐carvone, inhibit the human bitter taste receptors for saccharin and acesulfame K

FEBS Open Bio, EarlyView.
We report that some menthol‐like cooling compounds, including (R)‐(‐)‐carvone, act as inhibitors of TAS2R31 and TAS2R43, which are taste receptors responsible for the intrinsic bitter aftertastes of saccharin and acesulfame K. However, there was little correlation between the intensity of the cooling sensation and the potency of bitterness inhibition ...
Miyuu Saito, Takumi Misaka
wiley   +1 more source

Carigueya, seu Marsupiale Americanum. or, The anatomy of an opossum, dissected at Gresham-College by Edw. Tyson, M. D. Fellow of the College of Physicians, and of the Royal Society, and reader of anatomy at the Chyrurgeons-Hall, in London. [PDF]

Edward Tyson
openalex   +1 more source