Results 121 to 130 of about 2,244,425 (315)

Intercompartmental communication in senescence

FEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz, Eleanor J. Wind, Jixiang Leng, Myriam Gorospe   +3 more
wiley   +1 more source

Physician-suggested strategies for deimplementing low-value care in Swedish primary care: a qualitative analysis across system levels. [PDF]

Implement Sci Commun
Öfverström HA, Ingvarsson S, Rundgren EH, Roczniewska M, Hasson H, Nilsen P, von Thiele Schwarz U.   +6 more
europepmc   +1 more source

Presentation of \u3cem\u3eLinacre Quarterly\u3c/em\u3e Award [PDF]

, 1981
Catholic Physicians\u27 Guild
core   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Going the distance: a cross-sectional geospatial analysis quantifying province-wide inequities in travel-based access, and fragility of access to French-language primary care provided by family physicians in Ontario, Canada. [PDF]

BMJ Open
Belanger C, Timony PE, Bélizaire A, Desilets A, Fitzsimon JP, Gauthier AP, Godfrey L, Karunananthan S, Kehoe MacLeod K, Muray MN, Peixoto C, Bjerre LM.   +11 more
europepmc   +1 more source

Letters to the Editor [PDF]

, 1968
Catholic Physicians\u27 Guild
core   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Barriers to prescribing and insurance approval of SGLT2 inhibitors for heart failure: a mixed-methods study in Jordan. [PDF]

Front Pharmacol
Merdas ZJH, Abed A, Abu Assab M, Abu Dayyih W, Bustami M, Saudi LM, Shilbayeh SAR.   +6 more
europepmc   +1 more source

At the Crossroads of Time [PDF]

, 1967
Catholic Physicians\u27 Guild
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source