FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Resolutions Formulated at the 1985 NFCPG Convention, Honolulu, Hawaii [PDF]
, 1986 Catholic Physicians\u27 Guild
core +1 more source
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Exploring the Multidimensional Advantages of Productive Failure in Cultivating Clinical Thinking, Collaboration, Stress Management, and Learning Retention in Resident Physicians. [PDF]
Adv Med Educ PractDing Y +4 more
europepmc +1 more source
Book Reviews of Moral Clarity in the Nuclear Age by Michael Novak -- Our Right to Choose: Toward a New Ethic of Abortion by Beverly Wildung Harrison -- The Death Decision: Eight Experts Address the Legal and Ethical Issues Emerging on the Frontier of Today\u27s New Biology edited Leonard J. Nelson -- Challenge to Love: Gay and Lesbian Catholics in the Church edited by Robert Nugent [PDF]
, 1984 Catholic Physicians\u27 Guild
core +1 more source
Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
FEBS Open Bio, EarlyView.Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source
Qualitative study on physicians' acceptance of a clinical decision support system for anemia management in patients receiving hemodialysis. [PDF]
BMC Health Serv ResYang JY, Cheng SH, Kuo RN.
europepmc +1 more source