Results 81 to 90 of about 487,811 (259)
Medical knowledge is evolving rapidly and expanding exponentially. The lifespan of information is now only 70 days, and a deluge of knowledge is predicted, driven by advances in information technology, artificial intelligence, the availability of large ...
Hilary Hoey +6 more
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
An invitation to a special meeting at The College of Physicians of Philadelphia in which Marie Curie presented the Piezo-Electric Apparatus which she and her husband Pierre used in their early experiments with radium.
The College of Physicians of Philadelphia
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A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Who do physicians work for? [PDF]
This paper presents a thorough analysis of the issue of dual job holding among physicians. As the causes and implications of this phenomenon may well depend on the specific form of dual practice under consideration, we first introduce a typology of dual ...
Paula González, Ariadna García-Prado
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Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Background We sought to characterize how the term “missed opportunities” is reported in the literature in the context of immunization rates and to assess how missed opportunities can be operationalized.
Natalia Loskutova +5 more
doaj +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Catalogue of the alumni, officers and fellows, 1807-1880 [College of Physicians and Surgeons].
Copy 4 is interleaved with blank pages on which there are manuscript annotations most likely made when preparing the 1891 edition of the catalogue."The volume has been comp. by Dr. A.E.M.
Purdy, Alfred E. M. (Alfred Edgar Martindale), 1838-1913, comp. +2 more
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