Results 121 to 130 of about 514,529 (316)

Matrix Stiffness Directs Stemness Signatures in Breast Cancer

Advanced Healthcare Materials, EarlyView.
We built lab‐grown breast cancer models to study how the stiffness of the tumor's surroundings influences cancer behavior. Softer environments encouraged more stem‐like, drug‐resistant cells, while stiffer ones kept cells more differentiated. These findings show that tissue mechanics drive cancer diversity and drug resistance, offering new insights for
Chantal Kopecky, Elvis Pandzic, Sean Porazinski, J Justin Gooding, Kristopher A Kilian   +4 more
wiley   +1 more source

Modeling of CO₂ Efflux from Forest and Grassland Soils Depending on Weather Conditions

Soil Systems
Carbon dioxide (CO2) efflux from soil (or soil respiration, SR) is one of the most important yet variable characteristics of soil. When evaluating large areas, CO2 efflux modeling serves as a viable alternative to direct measurements.
Sergey Kivalov, Irina Kurganova, Sergey Bykhovets, Dmitriy Khoroshaev, Valentin Lopes de Gerenyu, Yiping Wu, Tatiana Myakshina, Yakov Kuzyakov, Irina Priputina   +8 more
doaj   +1 more source

Affinity‐Tuned Albumin Hitchhiking Extends the Bioorthogonal Capture Window in Pretargeting Radiotheranostics

Advanced Healthcare Materials, EarlyView.
Pharmacokinetic engineering of clickable radioligands was achieved via albumin hitchhiking approach within a pretargeted radiotheranostics delivery platform. This approach reduced rapid renal elimination, expanded bioorthogonal capture window, boosted tumor uptake by ∼3.5‐fold, and improved the tumor‐to‐liver ratio by ∼6‐fold.
Xie He, Nicholas L. Fletcher, Gayathri R. Ediriweera, Yifei Zhu, James Humphries, Christopher B. Howard, Jiazheng Wang, Craig A. Bell, Kristian Kempe, Kristofer J. Thurecht   +9 more
wiley   +1 more source

Preparation and physicochemical characterization of spray-dried and jet-milled microparticles containing bosentan hydrate for dry powder inhalation aerosols

, 2016
Hyo-Jung Lee,1 Ji-Hyun Kang,1 Hong-Goo Lee,1 Dong-Wook Kim,2 Yun-Seok Rhee,3 Ju-Young Kim,4 Eun-Seok Park,5 Chun-Woong Park1 1College of Pharmacy, Chungbuk National University, 2Department of Pharmaceutical Engineering, Cheongju University, Cheongju ...
Kim D, Rhee Y, Lee H, Kim J, Kang J, Park C, Park E   +6 more
core  

Isotretinoin-LIDOSE: 15 years of experience in acne therapy. A review

Consilium Medicum
Isotretinoin is a systemic retinoid and a vitamin A derivative. Since the 1980s, it has established itself as a highly effective treatment for severe acne.
Luiza R. Sakaniya, Evgeniya V. Dvoriankova, Zofia A. Niewozinska, Ksenia V. Badlueva, Ekaterina S. Andrienko, Tamara V. Beley, Irina M. Korsunskaya   +6 more
doaj   +1 more source

Mixed‐Metal Promotion in a Manganese‐Molybdenum Oxynitride as Catalyst to Integrate C─C and C─N Coupling Reactions for the Direct Synthesis of Acetonitrile from Syngas and Ammonia

Advanced Materials, EarlyView.
Transition metal oxy/carbo‐nitrides show great promise as catalysts for sustainable processes. A Mn‐Mo mixed‐metal oxynitride attains remarkable performance for the direct synthesis of acetonitrile, an important commodity chemical, via sequential C─N and C─C coupling from syngas (C1) and ammonia (N1) feedstocks.
M. Elena Martínez‐Monje, Wilson Henao, Tania Rodenas, Patricia Concepción, Virginia Pérez Dieste, Alexander Missyul, Giovanni Agostini, Gonzalo Prieto   +7 more
wiley   +1 more source

Physicochemical properties of soils.

, 2017
Physicochemical properties of soils.
Nan Huang (464390), Weiwei Wang (105069), Xiaojuan Chang (3719938), Yanlai Yao (3719935), Weiping Wang (210831), Fengxiang Zhu (2890865)   +5 more
core   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Frozen Zoo: a collection of permafrost samples containing viable protists and their viruses [PDF]

Biodiversity Data Journal, 2020
Stas Malavin, Lyubov Shmakova, Jean-Michel Claverie, Elizaveta Rivkina   +3 more
doaj   +3 more sources

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source