Results 101 to 110 of about 1,586,560 (241)
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang+7 more
wiley +1 more source
By using an electrical pulse stimulation (EPS)‐based in vitro exercise model and chemical activation/inhibition of mechanosensitive Piezo1 channels, we explored changes in protein synthetic response in cultured C2C12 myotubes. Our data showed that application of Piezo1 activator (Yoda1) during EPS significantly enhances the rate of protein synthesis in
Natalia A. Vilchinskaya+3 more
wiley +1 more source
Topological Aspects of Gauge Theories [PDF]
To appear in Encyclopedia of Mathematical Physics, published by Elsevier in early 2006. Comments/corrections welcome. The article surveys topological aspects in gauge theories.
arxiv
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik+3 more
wiley +1 more source
The document develops a brief introduction to the absence or obscuration of the epistemic doctrine of Francisco Suárez under a triple speculative restriction: 1.
José María Felipe Mendoza
doaj +1 more source
Possible role of human ribonuclease dicer in the regulation of R loops
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik+2 more
wiley +1 more source
Mała książka o wielkim wszechświecie
We live in extraordinary times for cosmologists. A vast amount of new astronomical data is pushing our model of the universe to its limits. An interest in cosmology is growing.
Sebastian Jan Szybka
doaj
Lessons From Astronomy and Biology for the Mind—Copernican Revolution in Neuroscience
Neuroscience made major progress in unravelling the neural basis of mental features like self, consciousness, affect, etc. However, we nevertheless lack what recently has been described as “missing ingredient” or “common currency” in the relationship ...
Georg Northoff
doaj +1 more source
Invariances in Physics and Group Theory [PDF]
This is a short review of the heritage of Klein's Erlangen program in modern physics.
arxiv
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel+3 more
wiley +1 more source