Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
New Challenges For Wind Shock Models: The Chandra Spectrum Of The Hot Star Delta Orionis [PDF]
The Chandra spectrum of delta Ori A shows emission lines from hydrogen- and helium-like states of Si, Mg, Ne, and O, along with N VII Lyalpha and lines from ions in the range Fe XVII-Fe XXI In contrast to the broad lines seen in zeta Pup and zeta Ori ...
Cassinelli, J. P. +4 more
core +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
On The Importance Of The Interclump Medium For Superionization: O VI Formation In The Wind Of Zeta Puppis [PDF]
We have studied superionization and X-ray line formation in the spectra of zeta Pup using our new stellar atmosphere code (XCMFGEN) that can be used to simultaneously analyze optical, UV, and X-ray observations.
Bouret, J.-C. +5 more
core +2 more sources
KELT-20b: A Giant Planet With A Period Of P ~ 3.5 Days Transiting The V ~ 7.6 Early A Star HD 185603 [PDF]
We report the discovery of KELT-20b, a hot Jupiter transiting a early A star, HD 185603, with an orbital period of days. Archival and follow-up photometry, Gaia parallax, radial velocities, Doppler tomography, and AO imaging were used to confirm the ...
Beatty, T. G. +56 more
core +3 more sources
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Chandra Spectroscopy Of The Hot Star β Crucis And The Discovery Of A Pre-Main-Sequence Companion [PDF]
In order to test the O star wind-shock scenario for X-ray production in less luminous stars with weaker winds, we made a pointed 74-ks observation of the nearby early B giant, beta Crucis (beta Cru; B0.5 III), with the Chandra High Energy Transmission ...
Cohen, David H. +4 more
core +1 more source
KELT-3b: A Hot Jupiter Transiting A V=9.8 Late-F Star [PDF]
We report the discovery of KELT-3b, a moderately inflated transiting hot Jupiter with a mass of 1.477(-0.067)(+0.066) M-J, radius of 1.345 +/- 0.072 R-J, and an orbital period of 2.7033904 +/- 0.000010 days.
Beatty, T. G. +33 more
core +2 more sources
What do we expect, as teachers, when selecting a text for our students: comprehension or readability? [PDF]
This paper analyzes the role that a group of college teachers of physics assigns to the comprehension of instructions and of concepts. Based on a text fragment, used to trigger answers, we discuss the "forms" that are attributed to the comprehension of ...
María Silvia Stipcich, Marta Massa
doaj
Emerging role of ARHGAP29 in melanoma cell phenotype switching
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source

