Results 71 to 80 of about 1,222,546 (268)

Epistemological beliefs and classroom practices of experienced physics teachers: are they related?

open access: yesFrontiers in Education
There is a need in teacher education to explore experienced physics teachers' domain-general epistemological beliefs and classroom practices. The study reports 30 experienced physics teachers' epistemological beliefs and classroom practices in Turkish ...
Ozden Sengul
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

PERSEPSI WISATAWAN TERHADAP FASILITAS WISATA DI PUSAT LATIHAN GAJAH TAMAN NASIONAL WAY KAMBAS

open access: yesJurnal Belantara, 2018
The growth of tourism is affected by the level of satisfication from the visitors towords the existence of tourism facilities.  The aim of this research is to know the visitors perspective towards the tourism facilities at Elephant Training Center of ...
shinta dewi marcelina   +3 more
doaj  

Cosmic Evolution Optimization: A Novel Metaheuristic Algorithm for Numerical Optimization and Engineering Design

open access: yesMathematics
This study proposes a novel metaheuristic algorithm, Cosmic Evolution Optimization (CEO), for numerical optimization and engineering design. Inspired by the cosmic evolution process, CEO simulates physical phenomena including cosmic expansion, universal ...
Rui Wang, Zhengxuan Jiang, Guowen Ding
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

CONTRIBUTIONS OF TIPLER'S OMEGA POINT THEORY

open access: yesZygon, 1995
. An attempt to discover what can be learned from the recent work of Frank Tipler on the Omega Point theory requires an analysis of his framework of understanding from scientific, philosophical, and theological perspectives.
doaj   +2 more sources

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