Results 11 to 20 of about 773,674 (244)

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

On the origin of the gravitational quantization: The Titius--Bode Law

open access: yes, 2005
Action at distance in Newtonian physics is replaced by finite propagation speeds in classical post--Newtonian physics. As a result, the differential equations of motion in Newtonian physics are replaced by functional differential equations, where the ...
Agnese   +29 more
core   +4 more sources

Precision Spectroscopy of Molecular Hydrogen Ions: Towards Frequency Metrology of Particle Masses [PDF]

open access: yes, 2006
We describe the current status of high-precision ab initio calculations of the spectra of molecular hydrogen ions (H_2^+ and HD^+) and of two experiments for vibrational spectroscopy.
Bakalov, D.   +6 more
core   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Incorporating Uncertainties in Atomic Data Into the Analysis of Solar and Stellar Observations: A Case Study in Fe XIII

open access: yes, 2018
Information about the physical properties of astrophysical objects cannot be measured directly but is inferred by interpreting spectroscopic observations in the context of atomic physics calculations. Ratios of emission lines, for example, can be used to
Cisewski-Kehe, Jessi   +8 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Metan Molekülünün Elektron Etkisiyle İyonlaşma Dinamiğinin Çakışma Tekniği ile İncelenmesi

open access: yesSüleyman Demirel Üniversitesi Fen-Edebiyat Fakültesi Fen Dergisi, 2014
Özet: Karmaşık moleküllerin elektronlarla etkileşimlerinin ayrıntılı bir biçimde anlaşılmasının atom ve molekül fiziği araştırmalarında, kuramsal modellemelerin gelişmesinde önemli bir yeri vardır. Özellikle moleküllerin dinamik yapılarının anlaşılmasına
Nimet IŞIK   +2 more
doaj  

Atomic and Molecular Physics [PDF]

open access: yes, 2019
Atoms are the basic building blocks of any material system: their physics rules over the behaviour of basically everything. Therefore, even if we limit ourselves to just consider what is found on our planet, the atomistic picture is really needed to understand at the most fundamental level the physical behaviour of organic and inorganic matter ...
openaire   +1 more source

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