Results 41 to 50 of about 1,659,003 (311)
Molecular Oncology, EarlyView.Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran +16 more
wiley +1 more source
Plasma-inspired biomaterials [PDF]
, 2017 The first questions which arise when one looks at the title of this special issue are what are plasma-inspired biomaterials, and what is this Special Issue of Journal of Physics D: Applied Physics (JPhysD) all about?
Canal Barnils, Cristina +2 more
core +2 more sources
PHYSICAL AND BIOLOGICAL OBSERVATIONS ON HERPESVIRUS [PDF]
Journal of Bacteriology, 1963 Smith, KendallO. (Baylor University College of Medicine, Houston, Texas). Physical and biological observations on herpesvirus. J. Bacteriol.86:999–1009. 1963.—The development of herpesvirus in human lung fibroblasts was studied by plaque assays and physical particle counts. Approximately 200 infectious units and 60,000 particles were produced by single
openaire +3 more sources
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
Molecular Oncology, EarlyView.We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas +15 more
wiley +1 more source
Evolutionary Dynamics of Populations with Conflicting Interactions: Classification and Analytical Treatment Considering Asymmetry and Power [PDF]
, 2010 Evolutionary game theory has been successfully used to investigate the dynamics of systems, in which many entities have competitive interactions.
Anders Johansson +19 more
core +1 more source
Molecular Oncology, EarlyView.Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien +7 more
wiley +1 more source
Is Physics Sick? [In Praise of Classical Physics] [PDF]
arXiv, 2012 In this paper, it is argued that theoretical physics is more akin to an organism than to a rigid structure.It is in this sense that the epithet, "sick", applies to it. It is argued that classical physics is a model of a healthy science, and the degree of sickness of modern physics is measured accordingly.
arxiv
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source
Modern Mathematical Physics: what it should be? [PDF]
arXiv, 2000 Personal view of author on goals and content of Mathematical Physics.
arxiv