Results 71 to 80 of about 1,258,930 (298)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Unbiased auxiliary basis sets for accurate two-electron integral approximations [PDF]

open access: yes, 2007
We propose Cholesky decomposition (CD) of the atomic two-electron integral matrix as a robust and general technique for generating auxiliary basis sets for the density fitting approximation.
Francesco Aquilante   +7 more
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Interrogating the Becke’05 density functional for non-locality information [PDF]

open access: yes, 2017
This document is the unedited Author's version of a Submitted Work that was subsequently accepted for publication in the Journal of Chemical Physics, copyright © American Institute of Physics after peer review.
Johnson, Erin   +2 more
core  

Erratum: Surfactant free fabrication of polyimide nanoparticles (Applied Physics Letters (2004) 85 (23)) [PDF]

open access: yes, 2010
10.1063/1.3476338Applied Physics Letters978 ...
Liu, X.Y.   +7 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Analytical study of contents of LANL physics and cross-listed e-print archives, 1994-2002 [PDF]

open access: yes, 2003
The frontiers of physics and cross-listed e-print archives posted during the years 1994-2002 at http://www.arxiv.org/archives/physics web service of Los Alamos National Laboratory (LANL) are explored from 7770 submissions.
Lalit Mohan, *   +6 more
core  

Tables of Physical and Chemical Constants

open access: yes, 2018
1. Units and Fundamental Constants: 1.1 Units. 1.2 Fundamental physical constants. 2. General Physics: 2.1 Measurements of mass, pressure and other mechanical quantities. 2.2 Mechanical properties of materials. 2.3 Temperature and heat. 2.4 Acoustics.
G. Kaye, T. H. Laby
semanticscholar   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Improving the Training of Pre-Service Physics Teachers in Malaysia using Didaktik Analysis [PDF]

open access: yes, 2008
The research in this thesis examined the use of a didaktik-based approach to thinking about teaching and learning to the training of pre-service physics teachers in a Malaysian teacher training programme.
Ishak, Mohd. Zaki
core  

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