Results 41 to 50 of about 177,098 (269)

A survey of computational physics: introductory computational science [PDF]

, 2008
Computational physics is a rapidly growing subfield of computational science, in large part because computers can solve previously intractable problems or simulate natural processes that do not have analytic solutions. The next step beyond Landau's First
Landau, Rubin H, Paez, Manuel José, Bordeianu, Cristian C   +2 more
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Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Les Houches 2015: Physics at TeV colliders - new physics working group report [PDF]

, 2016
We present the activities of the 'New Physics' working group for the 'Physics at TeV Colliders' workshop (Les Houches, France, 1-19 June, 2015). Our report includes new physics studies connected with the Higgs boson and its properties, direct search ...
Pollard, C, Zerwas, D, Krauss, ME, Ittisamai, P., Shao, H.-S., Katz, A., Orlando, R. D., Simmons, EH, Santiago, J., Laa, U., Papucci, M., Cai, H, Krauss, M.E., Simmons, E. H., Brooijmans, Gustaaf, Conte, E, Mühlleitner, M., Schmidt, T, Rizzo, T., Sanz, V, Nardecchia, M., Weiler, A, Nikitenko, S., Kulkarni, S, Waltenberger, W, Henrot-Versillé, S, Santiago, J, Brehmer, J., Sakurai, K., Porod, W, Majumder, D, Spira, M., Cai, H., Majumder, D., Quirós, M, You, T, Schmidt, T., Filippis, N. De, Hewett, JL, Kopp, J., Shao, H. -S., Papucci, M, Bernon, J., Ittisamai, P, Flacke, T., Sengupta, D., Lacroix, S, Mawatari, K, Brivio, I., Carmona, A, Rizzo, T, Sekmen, S, Laa, U, Mawatari, K., Unel, G., Carmona, Adrian, Gras, P, No, JM, No, J.M., Falkowski, A., Weiler, A., Pollard, C., Shao, H-S, Sekmen, S., Tattersall, J, Brivio, I, Deandrea, A., Morse, D. M., Garcia-Pepin, M, Kopp, J, Mohan, K, Lacroix, S., Mühlleitner, M, Mimasu, K, Mimasu, K., Barducci, D, Burns, D., Martin, A., Sakurai, K, Kulkarni, S., Buckley, A., Carmona, A., Zapata, OA, Cacciapaglia, G., Sanz, V., Fuks, B., Desai, N., Gleyzer, S., Burns, D, Carvalho, A, Barducci, D., Krauss, M. E., Brehmer, J, Hewett, J. L., Martin, A, Deandrea, A, Filippis, N De, Simmons, E.H., Hewett, J.L., Chivukula, R. S., Delgado, A., Tattersall, J., De Filippis, N., Kraml, S., Bernon, J, Buckley, A, Morse, DM, Delgado, A, Mohan, K., Chen, Y., Henrot-Versillé, S., Chivukula, RS, Gras, P., Zapata, O. A., Lane, Kenneth D., Prosper, HB, Brehmer, Johann, Nikitenko, S, Lane, K., Morse, D.M., Chalons, G., Goertz, F., Chivukula, R.S., Spieker, T., Carvalho, A., You, T., Englert, C, Cacciapaglia, G, Nardecchia, M, Schmeier, D, Goudelis, A, Polesello, G, Garcia-Pepin, M., Katz, A, Bharucha, A., Delaunay, C., Vega-Morales, R., Zapata, O.A., Gleyzer, S, Brooijmans, G, Chen, Y, Flacke, T, Kraml, S, Waltenberger, W., Falkowski, A, Unel, G, Lane, K, Schmeier, D., No, J. M., Frigerio, M, Orlando, RD, Conte, E., Frigerio, M., Polesello, G., Vega-Morales, R, Bharucha, A, Goudelis, A., Prosper, H.B., Sonneveld, J, Brooijmans, G., Goertz, F, Fuks, B, Bharucha, Aoife, Spira, M, Pani, P, Desai, N, Chalons, G, Spieker, T, Zerwas, D., Delaunay, C, Chivukula, Sekhar R., Orlando, R.D., Pani, P., Englert, C., Delgado, Antonio, Porod, W., Quirós, M., Sengupta, D, Sonneveld, J.   +178 more
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Basic concepts in computational physics [PDF]

, 2016
This new edition is a concise introduction to the basic methods of computational physics. Readers will discover the benefits of numerical methods for solving complex mathematical problems and for the direct simulation of physical processes.
Schachinger, Ewald, Stickler, Benjamin A
core   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

The physical limits of computing

Computing in Science & Engineering, 2002
Many of the fundamental limits on information processing, from thermodynamics, relativity, and quantum mechanics, are only a few decades away. Novel physically motivated computing paradigms, such as reversible computing and quantum computing, may help in certain ways, but even they remain subject to some basic limits.
openaire   +2 more sources

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Computational complexity and statistical physics [PDF]

, 2005
Computer science and physics have been closely linked since the birth of modern computing. In recent years, an interdisciplinary area has blossomed at the junction of these fields, connecting insights from statistical physics with basic computational ...
Percus, Allon, Moore, Cristopher, Istrate, Gabriel   +2 more
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