Results 51 to 60 of about 692,439 (328)
FEBS Letters, EarlyView.Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli +10 more
wiley +1 more source
Statistical and dynamical decoupling of the IGM from Dark Matter
, 2010 The mean mass densities of cosmic dark matter is larger than that of baryonic matter by a factor of about 5 in the $\Lambda$CDM universe. Therefore, the gravity on large scales should be dominant by the distribution of dark matter in the universe ...
Fang, Li-Zhi, Zhu, Weishan
core +2 more sources
Fundamental understanding of swirling flow pattern in hydrocyclones [PDF]
, 2012 This work is concerned with establishing and validating a physics-based model that describes the swirling flow inside hydrocyclones. The physics is embedded in a Computational Fluid Dynamics (CFD) simulation model whose key features are presented and ...
Bourgeois, Florent +2 more
core +1 more source
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
FEBS Letters, EarlyView.Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan +2 more
wiley +1 more source
Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes
FEBS Letters, EarlyView.Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley +1 more source
Oceananigans.jl: Fast and friendly geophysical fluid dynamics on GPUs
Journal of Open Source Software, 2020 Oceananigans.jl is a fast and friendly software package for the numerical simulation of incompressible, stratified, rotating fluid flows on CPUs and GPUs.
A. Ramadhan +9 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
A Unified Gas-kinetic Scheme for Continuum and Rarefied Flows IV: full Boltzmann and Model Equations
, 2016 Fluid dynamic equations are valid in their respective modeling scales. With a variation of the modeling scales, theoretically there should have a continuous spectrum of fluid dynamic equations. In order to study multiscale flow evolution efficiently, the
Cai, Qingdong +3 more
core +1 more source
Hydrodynamic flow in small systems or: “How the heck is it possible that a system emitting only a dozen particles can be described by fluid dynamics?” [PDF]
Journal of Physics: Conference Series, 2019 The “unreasonable effectiveness” of relativistic fluid dynamics in describing high energy heavy-ion and even proton-proton collisions will be demonstrated and discussed.
U. Heinz, J. Scott Moreland
semanticscholar +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source