Results 41 to 50 of about 2,440,502 (294)

Holographic Duals of Quark Gluon Plasmas with Unquenched Flavors

, 2011
We review the construction of gravitational solutions holographically dual to N=1 quiver gauge theories with dynamical flavor multiplets. We focus on the D3-D7 construction and consider the finite temperature, finite quark chemical potential case where ...
, A. Amariti, A. Amariti, A. Amariti, A. Batrachenko, A. Gadde, A. Karch, A. Karch, A. Paredes, A.L. Cotrone, A.V. Ramallo, Aldo Cotrone, B.A. Burrington, B.A. Burrington, C. Eling, C. Nunez, D. Arean, D. Arean, D. Mateos, D. Mateos, D. Mateos, D.T. Son, Daniel Mayerson, E. Caceres, E. Caceres, E. Conde, F. Benini, F. Benini, F. Benini, F. Bigazzi, F. Bigazzi, F. Bigazzi, F. Bigazzi, F. Bigazzi, F. Bigazzi, F. Bigazzi, F. Bigazzi, F. Canoura, Francesco Bigazzi, G. Bertoldi, H.Y. Chen, I. Kanitscheider, I.R. Klebanov, J. A. Minahan, J. Casalderrey-Solana, J. Erdmenger, J. Erdmenger, J. Gaillard, J. Mas, J. Schmude, J.M. Maldacena, Javier Mas, Javier Tarrio, K. Kajantie, K.Y. Kim, M. Mia, M. Mia, N. Horigome, O. Aharony, O. DeWolfe, O. DeWolfe, O. Lorente-Espin, O. Lunin, P. Kovtun, P. Romatschke, R. Baier, R. Casero, R.C. Myers, S. Bhattacharyya, S. Bhattacharyya, S. Kobayashi, S.S. Gubser, Y.H. Gao   +72 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Rotation and Spin in Physics

, 2010
We delineate the role of rotation and spin in physics, discussing in order Newtonian classical physics, special relativity, quantum mechanics, quantum electrodynamics and general relativity. In the latter case, we discuss the generalization of the Kepler
A Lawler, A Papapetrou, AP French, BM Barker, BM Barker, BM Barker, BM Barker, BM Barker, C Feiler, C Moller, DW Sciama, E Cartan, E Corinaldesi, FW Hehl, G Brumfiel, GE Uhlenbeck, H Goldstein, HC Corben, I Ciufolini, I Ciufolini, IH Stairs, JA Wheeler, JD Jackson, JG Williams, JG Williams, JJ Sakurai, L Chan, L Foldy, LD Landau, LH Thomas, M Hillery, M Kramer, ME Rose, PAM Dirac, R Utiyama, RF O’Connell, RF O’Connell, RF O’Connell, RF O’Connell, RF O’Connell, RF O’Connell, RF O’Connell, RF O’Connell, RP Breton, S Weinberg, SN Gupta, TD Newton, TWB Kibble, V Bargmann, VB Berestetskii   +49 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

New-Physics Effects on Triple-Product Correlations in Lambda_b Decays

, 2002
We adopt an effective-lagrangian approach to compute the new-physics contributions to T-violating triple-product correlations in charmless Lambda_b decays. We use factorization and work to leading order in the heavy-quark expansion.
A. Datta, A.Y. Smirnov, Alakabha Datta, B.C. Allanach, C.E. Carlson, D.K. Ghosh, David London, E. Nardi, G. Hiller, G. Valencia, H.Y. Cheng, I. Hinchliffe, J. Bernabéu, K. Hagiwara, K. Leroux, M. Gronau, S. Pakvasa, W. Bensalem, W. Bensalem, Wafia Bensalem, Y. Grossman, Y. Grossman, Y. Nir   +22 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source