Results 31 to 40 of about 2,706,964 (293)

Trends in Detector R&D [PDF]

, 2013
Detectors are they eyes with which we observe the physics and explore new phenomena. The development of more performing detectors is essential for future physics discoveries and requires appropriate attention, funding, and recognition.
FORTI, FRANCESCO
core   +1 more source

Application of Time Projection Chambers with GEMs and Pixels to WIMP Searches and Fast Neutron Detection

, 2012
We present work on the detection of neutral particles via nuclear recoils in gas-filled Time Projection Chambers (TPCs). We employ Gas Electron Multipliers (GEMs) to amplify the signal and silicon pixel electronics to detect the avalanche charge.
Feng, Haolu, Garcia-Sciveres, Maurice, Jaegle, Igal, Kadyk, John, Nguyen, Young, Rosen, Marc, Ross, Steven, Thorpe, Thomas, Vahsen, Sven, Yamaoka, Jared   +9 more
core   +1 more source

High-speed optical data transmission for detector instrumentation in particle physics

, 2020
This work discusses the advantage of optical transmission utilizing wavelength-division multiplexing for the read-out of experimental data in detector instrumentation in high-energy physics, astroparticle physics or photon science. A multi-channel optical transmitter is developed as the core component on a silicon-on-insulator platform.
openaire   +2 more sources

Forward Physics at the LHC [PDF]

, 2008
The CMS/TOTEM and ATLAS collaborations carry out a program of forward physics with several near-beam detectors extending their coverage to high pseudorapidities.
Rouby, Xavier
core   +1 more source

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

FEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche, John R. Riordan, Burkhard Tümmler   +2 more
wiley   +1 more source

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

Molecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke, Marie Tölle, Philipp Walter, Kira Meißner, Mara Goetz, Jolanthe Kropidlowski, Andreas W. Berger, Jakob R. Izbicki, Felix Nickel, Thilo Hackert, Klaus Pantel, Harriet Wikman, Faik G. Uzunoglu   +12 more
wiley   +1 more source

Instrument matrix of the four-detector photopolarimeter: physical meaning of its rows and columns and constraints on its elements

Annual Meeting Optical Society of America, 1988
The four-detector photopolarimeter (FDP) is an arrangement of four photodetectors for measuring the state of polarization of light. The output current vector I of the FDP is related to the input Stokes vector S by I = AS, where A is called the instrument matrix.
openaire   +3 more sources

Lowering the background level and the energy threshold of Micromegas x-ray detectors for axion searches

, 2015
Axion helioscopes search for solar axions by their conversion in x-rays in the presence of high magnetic fields. The use of low background x-ray detectors is an essential component contributing to the sensitivity of these searches.
Aune, S., Azmar. F., Castel, J.F., Dafni, T., Davenport, M., Ferrer-Ribas, E., Galan, J., Garcia, J.A., Garza, J.G., Giomataris, I., Iguaz, F.J., Irastorza, I.G., Jourde, D., Ortega, I., Papaevangelou, T., Rodriguez, A., Tomas, A., Vafeiadis, T., Yildiz, S.C.   +18 more
core   +2 more sources

Design of 280 GHz feedhorn-coupled TES arrays for the balloon-borne polarimeter SPIDER [PDF]

, 2016
We describe 280 GHz bolometric detector arrays that instrument the balloon-borne polarimeter SPIDER. A primary science goal of SPIDER is to measure the large-scale B-mode polarization of the cosmic microwave background in search of the cosmic-inflation ...
Austermann, Jason E., Beall, James A., Becker, Daniel T., Benton, Steven J., Bergman, A. Stevie, Bond, J. Richard, Bryan, Sean, Duff, Shannon M., Duivenvoorden, Adri J., Eriksen, H. K., Filippini, Jeffrey P., Fraisse, Aurelien A., Galloway, Mathew, Gambrel, Anne E., Ganga, K., Grigorian, Arpi L., Gualtieri, Riccardo, Gudmundsson, Jon E., Halpern, M., Hartley, John W., Hilton, Gene C., Hubmayr, Johannes, Jones, William C., McMahon, Jeffrey J., Moncelsi, Lorenzo, Nagy, Johanna M., Netterfield, C. B., Osherson, Benjamin, Padilla, Ivan, Racine, B., Rahlin, Alexandra S., Ruhl, John, Ruud, T. M., Shariff, J. A., Soler, J. D., Song, Xue, Ullom, Joel N., Van Lanen, Jeff, Vissers, Michael R., Wehus, I. K., Wen, Shyang, Wiebe, D. V., Young, Edward   +42 more
core   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source