Results 61 to 70 of about 9,598,617 (257)
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
High school students' perceptions of physics [PDF]
, 2010 viii, 221 leaves ; 29 cmThere are far fewer high school students enrolled in physics than in chemistry or biology courses within the province of Alberta (Alberta Education, 2007).
Checkley, Doug +1 more
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FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Training a physics teacher in the system of engineering and pedagogical education
Вестник Северо-Кавказского федерального университетаIntroduction. The article considers the problem of the development of engineering and pedagogical education and the training of physics teachers as engineering teachers, which is associated with improving the quality of mathematical, natural science and ...
N. A. Antonova
doaj +1 more source
Validity and reliability of an online test on the phenomena of reflection and refraction of sound
Apertura, 2019 This work presents the results of a validation and reliability process of a conceptual test on reflection and refraction phenomena of sound waves, a process that was carried out online using Knowledge Applied Technologies (TAC).
Jhonny Medina Paredes +2 more
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Discover Artificial IntelligenceGenerative artificial intelligence (GenAI) has garnered considerable attention across various disciplines, including physics education. Numerous studies have explored the potential of using these tools in physics education by assessing their ...
Natthawin Cho
doaj +1 more source
Education SciencesThis study focuses on interdisciplinary approaches within mathematics and physics education. Secondary schools, particularly those specialized in scientific curricula, have opportunities to explore common topics between mathematics and physics; however ...
Stefania Lippiello, Alessandra Boscolo
doaj +1 more source
JPPPF: Jurnal Penelitian & Pengembangan Pendidikan Fisika, 2019 This study investigates the effect of the use of teachers’ Lecture models combined with cooperative learning methods to improve students’ problem-solving skills in physics compare with the control group who were not exposed to the lecture model combined ...
Rahmi Putri Z +4 more
doaj +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source