Results 121 to 130 of about 645,349 (295)

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Gut cannabinoid receptor 1 regulates alcohol binge-induced intestinal permeability

eGastroenterology
Background Endocannabinoids acting via cannabinoid receptor 1 (CB1R) can elicit increased intestinal permeability (a condition also called ‘leaky gut’).
Bin Gao, Luca Maccioni, George Kunos, Szabolcs Dvorácskó, Grzegorz Godlewski, Resat Cinar, Malliga R Iyer   +6 more
doaj   +1 more source

THE PHYSIOLOGY OF INSECT DIAPAUSE. VII. THE RESPIRATORY METABOLISM OF THE CECROPIA SILKWORM DURING DIAPAUSE AND DEVELOPMENT

, 1953
Howard A. Schneiderman, Carroll M. Williams   +1 more
openalex   +2 more sources

ANATOMY AND PHYSIOLOGY OF THE TONSIL [PDF]

, 1909
Charles M. Robertson
openalex   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

THE PHYSIOLOGY OF THE IMMEDIATE REACTION OF ANAPHYLAXIS IN THE GUINEA-PIG

, 1910
John Auer, Paul A. Lewis
openalex   +1 more source

THE CULTURE, GENERAL PHYSIOLOGY, MORPHOLOGY, AND CLASSIFICATION OF THE NON-SULFUR PURPLE AND BROWN BACTERIA [PDF]

, 1944
C. B. van Niel
openalex   +1 more source

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

FEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang, Yuan Cao, Jing Du, Ying Zhang, Junxia Wang, Ying Yuan, Lianqing Sun   +6 more
wiley   +1 more source

Discussion on the Physiology of the Intra-Ocular Pressure [PDF]

, 1913
Greeves
openalex   +2 more sources

Recent Developments in Cell Physiology

, 1955
J. A. Kitching
openalex   +2 more sources