Results 181 to 190 of about 865,236 (332)

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

open access: yesFEBS Open Bio, EarlyView.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki   +11 more
wiley   +1 more source

Changes in goose hypothalamus under different photocycles: RNA-Seq reveals new pathways and molecules

open access: yesPoultry Science
Reproduction in avian species is regulated by light, and the hypothalamus is the most important regulator of the response to light signals. The objective of this study was to identify the key molecules and signaling pathways in the hypothalamus that ...
Yuyan FENG   +6 more
doaj  

Development of a personalized digital biomarker of vaccine-associated reactogenicity using wearable sensors and digital twin technology. [PDF]

open access: yesCommun Med (Lond)
Steinhubl SR   +10 more
europepmc   +1 more source

FEM1B enhances TRAIL‐induced apoptosis in T lymphocytes and monocytes

open access: yesFEBS Open Bio, EarlyView.
FEM1B facilitates TRAIL‐induced apoptosis through distinct mechanisms in T lymphocytes and monocytes. In T lymphocytes, FEM1B engages with TRAF2, leading to a reduction in TRAF2 expression, which subsequently lessens TRAF2's inhibitory influence on caspase‐8.
Chenbo Yang   +5 more
wiley   +1 more source

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

open access: yesFEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

Exploring longitudinal physiologic stress measurement and sleep quality interventions to improve psychological well-being in nurses: a pilot study. [PDF]

open access: yesHealth Psychol Behav Med
Norful AA   +7 more
europepmc   +1 more source

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