Results 201 to 210 of about 301,088 (265)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Evolution of advanced revascularization strategies for high-risk pulmonary embolism: a physiology-guided single-center experience. [PDF]

Front Cardiovasc Med
Greenspon LW, Whealon S, Bonn J, Caroline M, Gnall E.   +4 more
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Awake Flexible Scope Intubation in Critically Ill Patients With Physiologically Difficult Airways: A Prospective, Observational Case Series. [PDF]

Crit Care Explor
Camiré DCD, Ramaswamy TS, Chu LF, Mihm FG.   +3 more
europepmc   +1 more source

Wearable Data in Epilepsy Care. [PDF]

Epilepsy Curr
Aungaroon G.
europepmc   +1 more source