Results 251 to 260 of about 645,349 (295)

Identifying and mitigating the biological effectors of the social determinants of health in cancer. [PDF]

J Natl Cancer Inst
Wagner M, Benson CL, Obeng-Gyasi S, Conzen S, Mccullough LE, Halbert CH, Gerson SL.   +6 more
europepmc   +1 more source

LIN28B Promotes Cancer Cell Dissemination and Angiogenesis

Advanced Biology, EarlyView.
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo, Sara Menegazzo, Marcella Pantile, Silvia Bresolin, Carlo Zanon, Alessandro Davini, Massimiliano Mazzone, Alessandra Biffi, Sanja Aveic   +8 more
wiley   +1 more source

Unravelling the myriad physiologic roles of transthyretin: critical considerations for treating transthyretin amyloidosis. [PDF]

Ann Med
Gertz MA, Aras MA, Bart N, Brannagan TH, Griffin JM, Kontorovich AR, Rosen AM.   +6 more
europepmc   +1 more source

3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes

Advanced Biology, EarlyView.
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins, Ah Joung Yu, Cheryl T. Gomillion   +2 more
wiley   +1 more source

Quantifying physiological variability and improving reproducibility in 4D-flow MRI cerebrovascular measurements with self-supervised deep learning. [PDF]

Magn Reson Med
Jolicoeur BW, Yardim ZS, Roberts GS, Rivera-Rivera LA, Eisenmenger LB, Johnson KM.   +5 more
europepmc   +1 more source

Adipose Mesenchymal Stem Cell‐Derived Exosomes in Conjunction with Roflumilast Ameliorate Chronic Kidney Disease Through the Modulation of Fibrosis and Inflammation

Advanced Biology, EarlyView.
The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali, Mohamed H. Sherif, Nashwa Barakat, Bassant Yahia, Ahmed A. Shokeir, Basel Sitohy   +5 more
wiley   +1 more source

Cross-sectional study on the relationship between physiologic and mental health status and hypertension risk among oil workers in Xinjiang. [PDF]

Front Cardiovasc Med
Song Z, Ma X, Li X, Liu J.
europepmc   +1 more source

Infrared Neural Stimulation Elicits Distinct Molecular Pathways in Astrocytes Based on Laser Pulse Parameters

Advanced Biology, EarlyView.
Infrared (IR) light evokes distinct calcium and water transport responses in astrocytes, depending on stimulation duration and protocol. This study uses widefield imaging and pharmacology to reveal differential engagement of astroglial signaling pathways.
Wilson R. Adams, Ana I Borrachero‐Conejo, Pratheepa Kumari Rasiah, Emanuela Saracino, Roberto Zamboni, Eric Duco Jansen, Valentina Benfenati, Anita Mahadevan‐Jansen   +7 more
wiley   +1 more source

Topical Anesthesia During Minor Surgical and Needle-Related Procedures in Infants and Children. [PDF]

J Pediatr Pharmacol Ther
Tobias JD.
europepmc   +1 more source

Time-Domain Analysis of Low- and High-Frequency Near-Infrared Spectroscopy Sensor Technologies for Characterization of Cerebral Pressure-Flow and Oxygen Delivery Physiology: A Prospective Observational Study. [PDF]

Sensors (Basel)
Sainbhi AS, Vakitbilir N, Bergmann T, Stein KY, Hasan R, Silvaggio N, Hayat M, Moon J, Zeiler FA.   +8 more
europepmc   +1 more source